Mitral ring annuloplasty: An incomplete correction of functional mitral regurgitation associated with left ventricular remodeling

Justine Lachmann, Jamshid Shirani, Konstadinos A. Plestis, Robert W.M. Frater, Thierry H. LeJemtel

Research output: Contribution to journalArticlepeer-review

29 Scopus citations

Abstract

Functional mitral regurgitation (FMR) occurs commonly in patients undergoing left ventricular (LV) remodeling. It is ubiquitous in patients referred to cardiac transplantation for LV systolic dysfunction and predicts a poor prognosis. The LV remodeling that is responsible for FMR is well understood and involves regional LV dysfunction Mitral annular dilatation is present in patients with idiopathic dilated cardiomyopathy but most often absent in patients with ischemic cardiomyopathy. Nonrandomized observations indicate that implantation of a mitral undersized flexible mitral ring reduces the amount of FMR, reverses LV remodeling, and improves symptoms in patients with endstage cardiomyopathy and severe FMR. Whether a surgical procedure that does not correct the major LV alterations leading to FMR can have long-lasting effects on the amount of FMR and the reversal of LV remodeling remains to be demonstrated in randomized trials.

Original languageEnglish (US)
Pages (from-to)241-246
Number of pages6
JournalCurrent Cardiology Reports
Volume3
Issue number3
DOIs
StatePublished - 2001

All Science Journal Classification (ASJC) codes

  • Cardiology and Cardiovascular Medicine

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