Model of unequal chromosomal crossing over in DNA sequences

Nikolay Dokholyan, Sergey V. Buldyrev, Shlomo Havlin, H. Eugene Stanley

Research output: Contribution to journalArticlepeer-review

13 Scopus citations

Abstract

It is known that some dimeric tandem repeats (DTR) are very abundant in noncoding DNA. We find that certain DTR length distribution functions in noncoding DNA can be fit by a power law function. We analyze a simplified model of unequal chromosomal crossing over and find that it produces a stable power law length distribution function, with the exponent μ = 2. Although the exponent predicted by this model differs from those observed in nature, we argue that the biophysical process underlying this model provides the major contribution to the DTR length distribution function.

Original languageEnglish (US)
Pages (from-to)594-599
Number of pages6
JournalPhysica A: Statistical Mechanics and its Applications
Volume249
Issue number1-4
DOIs
StatePublished - Jan 2 1998

All Science Journal Classification (ASJC) codes

  • Statistics and Probability
  • Condensed Matter Physics

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