Modeling Exercises

Vida Abedi, Stefan Hoops, Raquel Hontecillas, Adria Carbo, Casandra Philipson, Monica Viladomiu, Andrew Leber, Pinyi Lu, Josep Bassaganya-Riera

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

Computational modeling techniques and tools are playing increasingly important roles in advancing a system-level mechanistic understanding of biological processes. The in silico experimentation can help shape and guide experimental and clinical efforts. There are an array of tools that can be used to accelerate creation of mathematical models and therefore facilitate generation of in silico simulations. In this chapter, we will briefly review some of these tools and provide hands-on modeling examples. Finally, the chapter proposes an examination of the relationship between model complexity, reliability and knowledge discovery, and model-driven hypothesis generation.

Original languageEnglish (US)
Title of host publicationComputational Immunology
Subtitle of host publicationModels and Tools
PublisherElsevier Inc.
Pages175-200
Number of pages26
ISBN (Electronic)9780128037157
ISBN (Print)9780128036976
DOIs
StatePublished - 2016

All Science Journal Classification (ASJC) codes

  • Medicine(all)

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