Modeling of multifunctional porous tissue scaffolds with continuous deposition path plan

Akm B. Khoda, Ibrahim Tarik Ozbolat, Bahattin Koc

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

A novel modeling technique for porous tissue scaffolds with targeting the functionally gradient variational porosity with continuous material deposition planning has been proposed. To vary the porosity of the designed scaffold functionally, medial axis transformation is used. The medial axis of each layers of the scaffold is calculated and used as an internal feature. The medial axis is then used connected to the outer contour using an optimum matching. The desired pore size and hence the porosity have been achieved by discretizing the sub-regions along its peripheral direction based on the pore size while meeting the tissue scaffold design constraints. This would ensure the truly porous nature of the structure in every direction as well as controllable porosity with interconnected pores. Thus the desired controlled variational porosity along the scaffold architecture has been achieved with the combination of two geometrically oriented consecutive layers. A continuous, interconnected and optimized tool-path has been generated for successive layers for additive-manufacturing or solid free form fabrication process. The proposed methodology has been computationally implemented with illustrative examples. Furthermore, the designed example scaffolds with the desired pore size and porosity has been fabricated with an extrusion based bio-fabrication process.

Original languageEnglish (US)
Title of host publicationASME 2012 International Mechanical Engineering Congress and Exposition, IMECE 2012
Pages571-577
Number of pages7
DOIs
StatePublished - Dec 1 2012
EventASME 2012 International Mechanical Engineering Congress and Exposition, IMECE 2012 - Houston, TX, United States
Duration: Nov 9 2012Nov 15 2012

Publication series

NameASME International Mechanical Engineering Congress and Exposition, Proceedings (IMECE)
Volume2

Other

OtherASME 2012 International Mechanical Engineering Congress and Exposition, IMECE 2012
CountryUnited States
CityHouston, TX
Period11/9/1211/15/12

Fingerprint

Porosity
Scaffolds
Pore size
3D printers
Layered manufacturing
Extrusion
Tissue Scaffolds
Planning
Fabrication

All Science Journal Classification (ASJC) codes

  • Mechanical Engineering

Cite this

Khoda, A. B., Ozbolat, I. T., & Koc, B. (2012). Modeling of multifunctional porous tissue scaffolds with continuous deposition path plan. In ASME 2012 International Mechanical Engineering Congress and Exposition, IMECE 2012 (pp. 571-577). (ASME International Mechanical Engineering Congress and Exposition, Proceedings (IMECE); Vol. 2). https://doi.org/10.1115/IMECE2012-86926
Khoda, Akm B. ; Ozbolat, Ibrahim Tarik ; Koc, Bahattin. / Modeling of multifunctional porous tissue scaffolds with continuous deposition path plan. ASME 2012 International Mechanical Engineering Congress and Exposition, IMECE 2012. 2012. pp. 571-577 (ASME International Mechanical Engineering Congress and Exposition, Proceedings (IMECE)).
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Khoda, AB, Ozbolat, IT & Koc, B 2012, Modeling of multifunctional porous tissue scaffolds with continuous deposition path plan. in ASME 2012 International Mechanical Engineering Congress and Exposition, IMECE 2012. ASME International Mechanical Engineering Congress and Exposition, Proceedings (IMECE), vol. 2, pp. 571-577, ASME 2012 International Mechanical Engineering Congress and Exposition, IMECE 2012, Houston, TX, United States, 11/9/12. https://doi.org/10.1115/IMECE2012-86926

Modeling of multifunctional porous tissue scaffolds with continuous deposition path plan. / Khoda, Akm B.; Ozbolat, Ibrahim Tarik; Koc, Bahattin.

ASME 2012 International Mechanical Engineering Congress and Exposition, IMECE 2012. 2012. p. 571-577 (ASME International Mechanical Engineering Congress and Exposition, Proceedings (IMECE); Vol. 2).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

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Khoda AB, Ozbolat IT, Koc B. Modeling of multifunctional porous tissue scaffolds with continuous deposition path plan. In ASME 2012 International Mechanical Engineering Congress and Exposition, IMECE 2012. 2012. p. 571-577. (ASME International Mechanical Engineering Congress and Exposition, Proceedings (IMECE)). https://doi.org/10.1115/IMECE2012-86926