Modifiable determinants of bone status in young women

Thomas Lloyd, T. J. Beck, H. M. Lin, Mark Tulchinsky, D. F. Eggli, T. L. Oreskovic, P. R. Cavanagh, E. Seeman

Research output: Contribution to journalArticle

51 Citations (Scopus)

Abstract

The purpose of this study was to evaluate the contributions of exercise, fitness, body composition, and calcium intake during adolescence to peak bone mineral density and bone structural measurements in young women. University Hospital and 75 healthy, white females in the longitudinal Penn State Young Women's Health Study were included. Body composition, total body, and hip bone mineral density (BMD) were measured by dual-energy X-ray absorptiometry (DXA), exercise scores by sports-exercise questionnaire during ages 12-18 years, and estimated aerobic capacity by bike ergometry. Section modulus values (a measurement of bending strength) cross-sectional area (CSA), subperiosteal width, and cortical thickness were calculated from DXA scan data for the femoral neck and femoral shaft. Calcium intakes were calculated from 39 days of prospective food records collected at 13 timepoints between ages 12 and 20 years; supplemental calcium intakes were included. Section moduli at the femoral neck and shaft were correlated significantly with lean body mass, sports-exercise scores (R2 = 0.07-0.19, p < 0.05), and aerobic capacity (R2 = 0.06-0.57, p < 0.05). Sports-exercise scores correlated with BMD at the femoral neck and shaft. Average total daily calcium intake at age 12-20 years ranged from 486 to 1958 mg/day and was not significantly associated with total or regional peak BMD or bone structure measures at 20 years of age. It was shown that achievable levels of exercise and fitness have a favorable effect on BMD and section modulus of the femoral neck and femoral shaft in young adult women, whereas daily calcium intake of >500 mg in female adolescents appears to have little, if any effect.

Original languageEnglish (US)
Pages (from-to)416-421
Number of pages6
JournalBone
Volume30
Issue number2
DOIs
StatePublished - Jan 1 2002

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Exercise
Bone and Bones
Femur Neck
Photon Absorptiometry
Body Composition
Calcium
Bone Density
Sports
Pelvic Bones
Ergometry
Women's Health
Thigh
Food
Surveys and Questionnaires

All Science Journal Classification (ASJC) codes

  • Endocrinology, Diabetes and Metabolism
  • Physiology
  • Histology

Cite this

Lloyd, T., Beck, T. J., Lin, H. M., Tulchinsky, M., Eggli, D. F., Oreskovic, T. L., ... Seeman, E. (2002). Modifiable determinants of bone status in young women. Bone, 30(2), 416-421. https://doi.org/10.1016/S8756-3282(01)00675-5
Lloyd, Thomas ; Beck, T. J. ; Lin, H. M. ; Tulchinsky, Mark ; Eggli, D. F. ; Oreskovic, T. L. ; Cavanagh, P. R. ; Seeman, E. / Modifiable determinants of bone status in young women. In: Bone. 2002 ; Vol. 30, No. 2. pp. 416-421.
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Lloyd, T, Beck, TJ, Lin, HM, Tulchinsky, M, Eggli, DF, Oreskovic, TL, Cavanagh, PR & Seeman, E 2002, 'Modifiable determinants of bone status in young women', Bone, vol. 30, no. 2, pp. 416-421. https://doi.org/10.1016/S8756-3282(01)00675-5

Modifiable determinants of bone status in young women. / Lloyd, Thomas; Beck, T. J.; Lin, H. M.; Tulchinsky, Mark; Eggli, D. F.; Oreskovic, T. L.; Cavanagh, P. R.; Seeman, E.

In: Bone, Vol. 30, No. 2, 01.01.2002, p. 416-421.

Research output: Contribution to journalArticle

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