Molecular cloning of a testis-specific gene from mouse chromosome 17

M. Kasahara, F. Figueroa, Jan Klein

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

A testis-specific gene located distal to Qa-2 was cloned from mouse chromosome 17. Although we still do not have any formal proof, several lines of evidence suggest that this gene might encode a testis-specific Pgk-2 isozyme. First, the tissue distribution of this gene is identical with that of Pgk-2. Second, the size of the 1-1-1 testicular transcript roughly coincides with that of the human X-linked PGK1. Third, 1-1-1 maps, like Pgk-2, distal to Qa-2. And fourth, in a preliminary survey of classical inbred strains, 1-1-1 detects restriction fragment length polymorphism concordant with the known allelic distribution of Pgk-2. DNA sequence information will provide a definite identification of this gene.

Original languageEnglish (US)
Pages (from-to)815-816
Number of pages2
JournalTransplantation proceedings
Volume19
Issue number1 I
StatePublished - Jan 1 1987

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Chromosomes, Human, Pair 17
Molecular Cloning
Testis
Genes
Tissue Distribution
Restriction Fragment Length Polymorphisms
Isoenzymes

All Science Journal Classification (ASJC) codes

  • Surgery
  • Transplantation

Cite this

Kasahara, M., Figueroa, F., & Klein, J. (1987). Molecular cloning of a testis-specific gene from mouse chromosome 17. Transplantation proceedings, 19(1 I), 815-816.
Kasahara, M. ; Figueroa, F. ; Klein, Jan. / Molecular cloning of a testis-specific gene from mouse chromosome 17. In: Transplantation proceedings. 1987 ; Vol. 19, No. 1 I. pp. 815-816.
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Kasahara, M, Figueroa, F & Klein, J 1987, 'Molecular cloning of a testis-specific gene from mouse chromosome 17', Transplantation proceedings, vol. 19, no. 1 I, pp. 815-816.

Molecular cloning of a testis-specific gene from mouse chromosome 17. / Kasahara, M.; Figueroa, F.; Klein, Jan.

In: Transplantation proceedings, Vol. 19, No. 1 I, 01.01.1987, p. 815-816.

Research output: Contribution to journalArticle

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Kasahara M, Figueroa F, Klein J. Molecular cloning of a testis-specific gene from mouse chromosome 17. Transplantation proceedings. 1987 Jan 1;19(1 I):815-816.