Monoclonal antibodies which recognize different cell types in the rat retina

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Abstract

Seven monoclonal antibodies have been produced against a membrane preparation from adult rat retina. Three antibodies reacted with particular regions of rat photoreceptor cell surfaces: RET-P1 labelled the cell bodies, outer and inner segments (rods but not cones), RET-P2 labelled only outer segments and RET-P3 labelled only the cell bodies. Three antibodies reacted with glial cells; RET-G2 and RET-G3 were specific for Müller cells, RET-G1 also labelled glia elsewhere in brain. The seventh antibody (RET-N1) reacted with many types of neuronal cells.

Original languageEnglish (US)
Pages (from-to)231-235
Number of pages5
JournalNature
Volume286
Issue number5770
DOIs
Publication statusPublished - Dec 1 1980

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