Monoclonal antibody-mediated neutralization of infectious human papillomavirus type 11

Neil Christensen, J. W. Kreider, N. M. Cladel, S. D. Patrick, P. A. Welsh

Research output: Contribution to journalArticlepeer-review

115 Scopus citations

Abstract

Monoclonal antibodies recognizing human papillomavirus type 11 (HPV-11) were prepared from BALB/c mice immunized with intact HPV-11 virions obtained from morphologically transformed human foreskin xenografts grown subrenally in athymic mice. Four of five monoclonal antibodies that were reactive by enzyme-linked immunosorbent assay only to intact virions neutralized HPV-11 infectivity in the athymic mouse xenograft system.

Original languageEnglish (US)
Pages (from-to)5678-5681
Number of pages4
JournalJournal of virology
Volume64
Issue number11
DOIs
StatePublished - 1990

All Science Journal Classification (ASJC) codes

  • Microbiology
  • Immunology
  • Insect Science
  • Virology

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