MONOZYGOTIC TWINS CONCORDANT FOR TRACHEO‐ESOPHAGEAL FISTULA AND DISCORDANT FOR THE VATER ASSOCIATION

SUSANNE L. KING, R. L. LADDA, S. J. SHOCHAT

Research output: Contribution to journalArticlepeer-review

20 Scopus citations

Abstract

Abstract. Monozygotic female twins were concordant for tracheo‐esophageal fistula (TEF); and one twin also manifested other anomalies of the VATER association, including agenesis of the female reproductive tract. Review of the literature discloses a familial tendency for recurrence of TEF and a high concordance rate in monozygotic twins, indicating a significant genetic influence for the isolated anomaly. In the case of the VATER association, the sporadic occurrence of affected individuals and discordance in twins implicates the effect of non‐genetic factors.

Original languageEnglish (US)
Pages (from-to)783-785
Number of pages3
JournalActa Pædiatrica
Volume66
Issue number6
DOIs
StatePublished - Dec 1977

All Science Journal Classification (ASJC) codes

  • Pediatrics, Perinatology, and Child Health

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