Abstract. Monozygotic female twins were concordant for tracheo‐esophageal fistula (TEF); and one twin also manifested other anomalies of the VATER association, including agenesis of the female reproductive tract. Review of the literature discloses a familial tendency for recurrence of TEF and a high concordance rate in monozygotic twins, indicating a significant genetic influence for the isolated anomaly. In the case of the VATER association, the sporadic occurrence of affected individuals and discordance in twins implicates the effect of non‐genetic factors.
|Original language||English (US)|
|Number of pages||3|
|State||Published - Dec 1977|
All Science Journal Classification (ASJC) codes
- Pediatrics, Perinatology, and Child Health