Mothers' dopamine receptor polymorphism modulates the relation between infant fussiness and sensitive parenting

Marsha Kaitz, Idan Shalev, Noam Sapir, Noa Devor, Yekutiel Samet, David Mankuta, Richard P. Ebstein

Research output: Contribution to journalArticle

19 Citations (Scopus)

Abstract

We determined whether the combination of the 48-bp variable number tandem repeat polymorphism of the dopamine (DRD4) gene and infants' (fussy-difficult) temperament predicted parenting sensitivity. The sample was comprised of 147 mothers and their 6-month olds. Sensitive parenting was assessed by coding filmed interactions between mothers and infants. Infant temperament was assessed by parents' reports on a standard questionnaire. Moderated regressions models, with maternal education and infants' interactive behavior as controls, were used to test our hypotheses. Results showed no main effects of either temperament or DRD4, though the maternal DRD4 × infant temperament interaction was significant. Probes indicated that parents with a DRD4 7-repeat allele behaved more sensitively to fussier infants and less sensitively to less fussy infants compared to parents without the 7-repeat allele. Among those parents, sensitivity did not vary with infant temperament. This pattern of results indicates that mothers are differentially susceptible to infant fussiness, dependent on the presence of the 7-repeat DRD4 allele.

Original languageEnglish (US)
Pages (from-to)149-157
Number of pages9
JournalDevelopmental psychobiology
Volume52
Issue number2
DOIs
StatePublished - Mar 1 2010

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Parenting
Dopamine Receptors
Temperament
Mothers
Parents
Alleles
Infant Behavior
Mother-Child Relations
Minisatellite Repeats
Behavior Control
Dopamine
Education
Genes

All Science Journal Classification (ASJC) codes

  • Developmental and Educational Psychology
  • Developmental Neuroscience
  • Developmental Biology
  • Behavioral Neuroscience

Cite this

Kaitz, Marsha ; Shalev, Idan ; Sapir, Noam ; Devor, Noa ; Samet, Yekutiel ; Mankuta, David ; Ebstein, Richard P. / Mothers' dopamine receptor polymorphism modulates the relation between infant fussiness and sensitive parenting. In: Developmental psychobiology. 2010 ; Vol. 52, No. 2. pp. 149-157.
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Mothers' dopamine receptor polymorphism modulates the relation between infant fussiness and sensitive parenting. / Kaitz, Marsha; Shalev, Idan; Sapir, Noam; Devor, Noa; Samet, Yekutiel; Mankuta, David; Ebstein, Richard P.

In: Developmental psychobiology, Vol. 52, No. 2, 01.03.2010, p. 149-157.

Research output: Contribution to journalArticle

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