Multi-gradient echo with susceptibility inhomogeneity compensation (MGESIC): Demonstration of fMRI in the olfactory cortex at 3.0 T

Qing Yang, Bernard J. Dardzinski, Shizhe Li, Paul Eslinger, Michael B. Smith

Research output: Contribution to journalArticle

95 Citations (Scopus)

Abstract

Short image acquisition times and sensitivity to magnetic susceptibility favor the use of gradient echo imaging methods in functional MRI (fMRI). However, magnetic susceptibility effects attributed to air-tissue interfaces also lead to severe signal loss in images of the large inferior frontal and lateral temporal cortices of the human brain, which renders these regions inaccessible to fMRI. The signal loss is caused by the local field gradients in the slice selection direction. A multigradient echo with magnetic susceptibility inhomogeneity compensation method (MGESIC) is proposed to overcome this problem. The MGESIC method effectively corrects the susceptibility artifacts and maintains the advantages of gradient echo methods to both BOLD sensitivity and fast image acquisition. The effectiveness of the MGESIC method is demonstrated by fMRI experimental results within the olfactory cortex.

Original languageEnglish (US)
Pages (from-to)331-335
Number of pages5
JournalMagnetic Resonance in Medicine
Volume37
Issue number3
DOIs
StatePublished - Mar 1 1997

Fingerprint

Magnetic Resonance Imaging
Temporal Lobe
Artifacts
Air
Olfactory Cortex
Brain

All Science Journal Classification (ASJC) codes

  • Radiology Nuclear Medicine and imaging

Cite this

@article{c5a0959ea78f4f628e1f54ca6e085c38,
title = "Multi-gradient echo with susceptibility inhomogeneity compensation (MGESIC): Demonstration of fMRI in the olfactory cortex at 3.0 T",
abstract = "Short image acquisition times and sensitivity to magnetic susceptibility favor the use of gradient echo imaging methods in functional MRI (fMRI). However, magnetic susceptibility effects attributed to air-tissue interfaces also lead to severe signal loss in images of the large inferior frontal and lateral temporal cortices of the human brain, which renders these regions inaccessible to fMRI. The signal loss is caused by the local field gradients in the slice selection direction. A multigradient echo with magnetic susceptibility inhomogeneity compensation method (MGESIC) is proposed to overcome this problem. The MGESIC method effectively corrects the susceptibility artifacts and maintains the advantages of gradient echo methods to both BOLD sensitivity and fast image acquisition. The effectiveness of the MGESIC method is demonstrated by fMRI experimental results within the olfactory cortex.",
author = "Qing Yang and Dardzinski, {Bernard J.} and Shizhe Li and Paul Eslinger and Smith, {Michael B.}",
year = "1997",
month = "3",
day = "1",
doi = "10.1002/mrm.1910370304",
language = "English (US)",
volume = "37",
pages = "331--335",
journal = "Magnetic Resonance in Medicine",
issn = "0740-3194",
publisher = "John Wiley and Sons Inc.",
number = "3",

}

Multi-gradient echo with susceptibility inhomogeneity compensation (MGESIC) : Demonstration of fMRI in the olfactory cortex at 3.0 T. / Yang, Qing; Dardzinski, Bernard J.; Li, Shizhe; Eslinger, Paul; Smith, Michael B.

In: Magnetic Resonance in Medicine, Vol. 37, No. 3, 01.03.1997, p. 331-335.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Multi-gradient echo with susceptibility inhomogeneity compensation (MGESIC)

T2 - Demonstration of fMRI in the olfactory cortex at 3.0 T

AU - Yang, Qing

AU - Dardzinski, Bernard J.

AU - Li, Shizhe

AU - Eslinger, Paul

AU - Smith, Michael B.

PY - 1997/3/1

Y1 - 1997/3/1

N2 - Short image acquisition times and sensitivity to magnetic susceptibility favor the use of gradient echo imaging methods in functional MRI (fMRI). However, magnetic susceptibility effects attributed to air-tissue interfaces also lead to severe signal loss in images of the large inferior frontal and lateral temporal cortices of the human brain, which renders these regions inaccessible to fMRI. The signal loss is caused by the local field gradients in the slice selection direction. A multigradient echo with magnetic susceptibility inhomogeneity compensation method (MGESIC) is proposed to overcome this problem. The MGESIC method effectively corrects the susceptibility artifacts and maintains the advantages of gradient echo methods to both BOLD sensitivity and fast image acquisition. The effectiveness of the MGESIC method is demonstrated by fMRI experimental results within the olfactory cortex.

AB - Short image acquisition times and sensitivity to magnetic susceptibility favor the use of gradient echo imaging methods in functional MRI (fMRI). However, magnetic susceptibility effects attributed to air-tissue interfaces also lead to severe signal loss in images of the large inferior frontal and lateral temporal cortices of the human brain, which renders these regions inaccessible to fMRI. The signal loss is caused by the local field gradients in the slice selection direction. A multigradient echo with magnetic susceptibility inhomogeneity compensation method (MGESIC) is proposed to overcome this problem. The MGESIC method effectively corrects the susceptibility artifacts and maintains the advantages of gradient echo methods to both BOLD sensitivity and fast image acquisition. The effectiveness of the MGESIC method is demonstrated by fMRI experimental results within the olfactory cortex.

UR - http://www.scopus.com/inward/record.url?scp=0031029807&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0031029807&partnerID=8YFLogxK

U2 - 10.1002/mrm.1910370304

DO - 10.1002/mrm.1910370304

M3 - Article

C2 - 9055220

AN - SCOPUS:0031029807

VL - 37

SP - 331

EP - 335

JO - Magnetic Resonance in Medicine

JF - Magnetic Resonance in Medicine

SN - 0740-3194

IS - 3

ER -