Multi-parameter hopf-bifurcation in HHM model exposed to ELF electric field

Jiang Wang, Yanqiu Che, Xiangyang Fei, Feng Dong

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

The variation of cell trans-membrane voltage exposed to extremely low frequency (ELF) electric field is analyzed; a modified Hodgkin-Huxley model of muscle (HHM) is established by introducing a new parameter denoting the effect of external electric field, and the bifurcation caused by the new parameter as well as leakage conductance and sodium ions anti-electromotive force is studied. The algebra criterion in high dimension equations is employed to perform the analysis of multi-parameter dynamical bifurcation. The results are of biological significance and suggest that the aberration of dynamics in bio-systems may be accounted for diseases caused by electric exposure.

Original languageEnglish (US)
Title of host publicationProceedings of the 2005 27th Annual International Conference of the Engineering in Medicine and Biology Society, IEEE-EMBS 2005
Pages4646-4649
Number of pages4
StatePublished - Dec 1 2005
Event2005 27th Annual International Conference of the Engineering in Medicine and Biology Society, IEEE-EMBS 2005 - Shanghai, China
Duration: Sep 1 2005Sep 4 2005

Publication series

NameAnnual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings
Volume7 VOLS
ISSN (Print)0589-1019

Other

Other2005 27th Annual International Conference of the Engineering in Medicine and Biology Society, IEEE-EMBS 2005
CountryChina
CityShanghai
Period9/1/059/4/05

All Science Journal Classification (ASJC) codes

  • Signal Processing
  • Biomedical Engineering
  • Computer Vision and Pattern Recognition
  • Health Informatics

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