Multimodality Image Fusion and Planning and Dose Delivery for Radiation Therapy

Cheng B. Saw, Hungcheng Chen, Ron E. Beatty, Henry Wagner

Research output: Contribution to journalArticle

9 Citations (Scopus)

Abstract

Image-guided radiation therapy (IGRT) relies on the quality of fused images to yield accurate and reproducible patient setup prior to dose delivery. The registration of 2 image datasets can be characterized as hardware-based or software-based image fusion. Hardware-based image fusion is performed by hybrid scanners that combine 2 distinct medical imaging modalities such as positron emission tomography (PET) and computed tomography (CT) into a single device. In hybrid scanners, the patient maintains the same position during both studies making the fusion of image data sets simple. However, it cannot perform temporal image registration where image datasets are acquired at different times. On the other hand, software-based image fusion technique can merge image datasets taken at different times or with different medical imaging modalities. Software-based image fusion can be performed either manually, using landmarks, or automatically. In the automatic image fusion method, the best fit is evaluated using mutual information coefficient. Manual image fusion is typically performed at dose planning and for patient setup prior to dose delivery for IGRT. The fusion of orthogonal live radiographic images taken prior to dose delivery to digitally reconstructed radiographs will be presented. Although manual image fusion has been routinely used, the use of fiducial markers has shortened the fusion time. Automated image fusion should be possible for IGRT because the image datasets are derived basically from the same imaging modality, resulting in further shortening the fusion time. The advantages and limitations of both hardware-based and software-based image fusion methodologies are discussed.

Original languageEnglish (US)
Pages (from-to)149-155
Number of pages7
JournalMedical Dosimetry
Volume33
Issue number2
DOIs
StatePublished - Jun 1 2008

Fingerprint

planning
Image-Guided Radiotherapy
radiation therapy
delivery
Radiotherapy
fusion
Software
dosage
Diagnostic Imaging
Fiducial Markers
Datasets
computer programs
Equipment and Supplies
hardware
scanners
tomography
landmarks
markers

All Science Journal Classification (ASJC) codes

  • Radiological and Ultrasound Technology
  • Oncology
  • Radiology Nuclear Medicine and imaging

Cite this

Saw, Cheng B. ; Chen, Hungcheng ; Beatty, Ron E. ; Wagner, Henry. / Multimodality Image Fusion and Planning and Dose Delivery for Radiation Therapy. In: Medical Dosimetry. 2008 ; Vol. 33, No. 2. pp. 149-155.
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Multimodality Image Fusion and Planning and Dose Delivery for Radiation Therapy. / Saw, Cheng B.; Chen, Hungcheng; Beatty, Ron E.; Wagner, Henry.

In: Medical Dosimetry, Vol. 33, No. 2, 01.06.2008, p. 149-155.

Research output: Contribution to journalArticle

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