Multiple complex congenital malformations in a rabbit kit (Oryctolagus cuniculi)

Jennifer Booth, Xuwen Peng, Jennifer Baccon, Timothy Cooper

Research output: Contribution to journalArticle

Abstract

Congenital malformations may occur during early embryogenesis in cases of genetic abnormalities or various environmental factors. Affected subjects most often have only one or 2 abnormalities; subjects rarely have several unrelated congenital defects. Here we describe a case of a stillborn New Zealand white rabbit with multiple complex congenital malformations, including synophthalmia, holoprosencephaly, gastroschisis, and a supernumerary hindlimb, among other anomalies. There was no historical exposure to teratogens or other known environmental causes. Although not confirmed, this case was most likely a rare spontaneous genetic event.

Original languageEnglish (US)
Pages (from-to)342-347
Number of pages6
JournalComparative Medicine
Volume63
Issue number4
StatePublished - Aug 1 2013

Fingerprint

Holoprosencephaly
Gastroschisis
congenital abnormalities
Teratogens
Oryctolagus cuniculus
Hindlimb
Embryonic Development
rabbits
teratogens
Rabbits
Defects
New Zealand White rabbit
embryogenesis
environmental factors
hindlimbs

All Science Journal Classification (ASJC) codes

  • Biochemistry, Genetics and Molecular Biology(all)
  • veterinary(all)

Cite this

@article{440b5c5b02ae4909b8e696d3e85ed3d8,
title = "Multiple complex congenital malformations in a rabbit kit (Oryctolagus cuniculi)",
abstract = "Congenital malformations may occur during early embryogenesis in cases of genetic abnormalities or various environmental factors. Affected subjects most often have only one or 2 abnormalities; subjects rarely have several unrelated congenital defects. Here we describe a case of a stillborn New Zealand white rabbit with multiple complex congenital malformations, including synophthalmia, holoprosencephaly, gastroschisis, and a supernumerary hindlimb, among other anomalies. There was no historical exposure to teratogens or other known environmental causes. Although not confirmed, this case was most likely a rare spontaneous genetic event.",
author = "Jennifer Booth and Xuwen Peng and Jennifer Baccon and Timothy Cooper",
year = "2013",
month = "8",
day = "1",
language = "English (US)",
volume = "63",
pages = "342--347",
journal = "Comparative Medicine",
issn = "1532-0820",
publisher = "American Association for Laboratory Animal Science",
number = "4",

}

Multiple complex congenital malformations in a rabbit kit (Oryctolagus cuniculi). / Booth, Jennifer; Peng, Xuwen; Baccon, Jennifer; Cooper, Timothy.

In: Comparative Medicine, Vol. 63, No. 4, 01.08.2013, p. 342-347.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Multiple complex congenital malformations in a rabbit kit (Oryctolagus cuniculi)

AU - Booth, Jennifer

AU - Peng, Xuwen

AU - Baccon, Jennifer

AU - Cooper, Timothy

PY - 2013/8/1

Y1 - 2013/8/1

N2 - Congenital malformations may occur during early embryogenesis in cases of genetic abnormalities or various environmental factors. Affected subjects most often have only one or 2 abnormalities; subjects rarely have several unrelated congenital defects. Here we describe a case of a stillborn New Zealand white rabbit with multiple complex congenital malformations, including synophthalmia, holoprosencephaly, gastroschisis, and a supernumerary hindlimb, among other anomalies. There was no historical exposure to teratogens or other known environmental causes. Although not confirmed, this case was most likely a rare spontaneous genetic event.

AB - Congenital malformations may occur during early embryogenesis in cases of genetic abnormalities or various environmental factors. Affected subjects most often have only one or 2 abnormalities; subjects rarely have several unrelated congenital defects. Here we describe a case of a stillborn New Zealand white rabbit with multiple complex congenital malformations, including synophthalmia, holoprosencephaly, gastroschisis, and a supernumerary hindlimb, among other anomalies. There was no historical exposure to teratogens or other known environmental causes. Although not confirmed, this case was most likely a rare spontaneous genetic event.

UR - http://www.scopus.com/inward/record.url?scp=84883785226&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84883785226&partnerID=8YFLogxK

M3 - Article

C2 - 24209970

AN - SCOPUS:84883785226

VL - 63

SP - 342

EP - 347

JO - Comparative Medicine

JF - Comparative Medicine

SN - 1532-0820

IS - 4

ER -