Multisubstrate analogue based on 5,8,10-trideazafolate

Dale L. Boger, Nancy Ellen Haynes, Mark S. Warren, Joseph Ramcharan, Paul A. Kitos, Stephen J. Benkovic

Research output: Contribution to journalArticle

17 Citations (Scopus)

Abstract

The preparation and evaluation of the multisubstrate analogue 3 based on the 5,8,10-trideazafolate core for GAR and AICAR Tfase inhibition is detailed.

Original languageEnglish (US)
Pages (from-to)1853-1857
Number of pages5
JournalBioorganic and Medicinal Chemistry
Volume5
Issue number9
DOIs
StatePublished - Sep 1 1997

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AICA ribonucleotide

All Science Journal Classification (ASJC) codes

  • Biochemistry
  • Molecular Medicine
  • Molecular Biology
  • Pharmaceutical Science
  • Drug Discovery
  • Clinical Biochemistry
  • Organic Chemistry

Cite this

Boger, D. L., Haynes, N. E., Warren, M. S., Ramcharan, J., Kitos, P. A., & Benkovic, S. J. (1997). Multisubstrate analogue based on 5,8,10-trideazafolate. Bioorganic and Medicinal Chemistry, 5(9), 1853-1857. https://doi.org/10.1016/S0968-0896(97)00124-7
Boger, Dale L. ; Haynes, Nancy Ellen ; Warren, Mark S. ; Ramcharan, Joseph ; Kitos, Paul A. ; Benkovic, Stephen J. / Multisubstrate analogue based on 5,8,10-trideazafolate. In: Bioorganic and Medicinal Chemistry. 1997 ; Vol. 5, No. 9. pp. 1853-1857.
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Boger, DL, Haynes, NE, Warren, MS, Ramcharan, J, Kitos, PA & Benkovic, SJ 1997, 'Multisubstrate analogue based on 5,8,10-trideazafolate', Bioorganic and Medicinal Chemistry, vol. 5, no. 9, pp. 1853-1857. https://doi.org/10.1016/S0968-0896(97)00124-7

Multisubstrate analogue based on 5,8,10-trideazafolate. / Boger, Dale L.; Haynes, Nancy Ellen; Warren, Mark S.; Ramcharan, Joseph; Kitos, Paul A.; Benkovic, Stephen J.

In: Bioorganic and Medicinal Chemistry, Vol. 5, No. 9, 01.09.1997, p. 1853-1857.

Research output: Contribution to journalArticle

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AU - Kitos, Paul A.

AU - Benkovic, Stephen J.

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Boger DL, Haynes NE, Warren MS, Ramcharan J, Kitos PA, Benkovic SJ. Multisubstrate analogue based on 5,8,10-trideazafolate. Bioorganic and Medicinal Chemistry. 1997 Sep 1;5(9):1853-1857. https://doi.org/10.1016/S0968-0896(97)00124-7