Multisubstrate analogue based on 5,8,10-trideazafolate

Dale L. Boger, Nancy Ellen Haynes, Mark S. Warren, Joseph Ramcharan, Paul A. Kitos, Stephen J. Benkovic

Research output: Contribution to journalArticle

17 Scopus citations

Abstract

The preparation and evaluation of the multisubstrate analogue 3 based on the 5,8,10-trideazafolate core for GAR and AICAR Tfase inhibition is detailed.

Original languageEnglish (US)
Pages (from-to)1853-1857
Number of pages5
JournalBioorganic and Medicinal Chemistry
Volume5
Issue number9
DOIs
StatePublished - Sep 1 1997

All Science Journal Classification (ASJC) codes

  • Biochemistry
  • Molecular Medicine
  • Molecular Biology
  • Pharmaceutical Science
  • Drug Discovery
  • Clinical Biochemistry
  • Organic Chemistry

Fingerprint Dive into the research topics of 'Multisubstrate analogue based on 5,8,10-trideazafolate'. Together they form a unique fingerprint.

  • Cite this

    Boger, D. L., Haynes, N. E., Warren, M. S., Ramcharan, J., Kitos, P. A., & Benkovic, S. J. (1997). Multisubstrate analogue based on 5,8,10-trideazafolate. Bioorganic and Medicinal Chemistry, 5(9), 1853-1857. https://doi.org/10.1016/S0968-0896(97)00124-7