Muscle biopsy in the evaluation of patients with modestly elevated creatine kinase levels

Zachary Simmons, B. Lee Peterlin, Philip J. Boyer, Javad Towfighi

Research output: Contribution to journalArticle

33 Citations (Scopus)

Abstract

The utility of muscle biopsy in patients with modest elevations of serum creatine kinase (CK) level but normal neurological examinations and nondiagnostic electrodiagnostic studies is uncertain. We performed systematic, extensive studies on muscle biopsies of 20 such patients. A definitive diagnosis was arrived at in only 1 by histochemical studies, although 4 others demonstrated minor myopathic changes. Biochemical evaluation led to a diagnosis in an additional 5. Muscle biopsy is useful for evaluating such patients, but extensive studies of the muscle are necessary.

Original languageEnglish (US)
Pages (from-to)242-244
Number of pages3
JournalMuscle and Nerve
Volume27
Issue number2
DOIs
StatePublished - Feb 1 2003

Fingerprint

Creatine Kinase
Biopsy
Muscles
Neurologic Examination
Serum

All Science Journal Classification (ASJC) codes

  • Physiology
  • Clinical Neurology
  • Cellular and Molecular Neuroscience
  • Physiology (medical)

Cite this

Simmons, Zachary ; Peterlin, B. Lee ; Boyer, Philip J. ; Towfighi, Javad. / Muscle biopsy in the evaluation of patients with modestly elevated creatine kinase levels. In: Muscle and Nerve. 2003 ; Vol. 27, No. 2. pp. 242-244.
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Muscle biopsy in the evaluation of patients with modestly elevated creatine kinase levels. / Simmons, Zachary; Peterlin, B. Lee; Boyer, Philip J.; Towfighi, Javad.

In: Muscle and Nerve, Vol. 27, No. 2, 01.02.2003, p. 242-244.

Research output: Contribution to journalArticle

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