Myelofibrosis involving lymph node: A novel cytogenetic abnormality in a mimicker of mesenchymal neoplasm

Youjun Hu, Ann Leslie Zaslav, Neetu Radhakrishnan, Marc Golightly, Colette Pameijer

Research output: Contribution to journalArticlepeer-review

1 Scopus citations

Abstract

A case of primary myelofibrosis involving lymph node and with a novel cytogenetic abnormality [del (18) (p11.2-3)] is reported. The abnormalities are identical among specimens from the lymph node, peripheral blood, and bone marrow that were analyzed years apart. Additionally, we show that the infiltrate by dysplastic megakaryocytes in the lymph node morphologically mimics a metastatic mesenchymal neoplasm, even when the clinical history myelofibrosis was known.

Original languageEnglish (US)
Pages (from-to)157-161
Number of pages5
JournalJournal of Hematopathology
Volume2
Issue number3
DOIs
StatePublished - 2009

All Science Journal Classification (ASJC) codes

  • Pathology and Forensic Medicine
  • Histology
  • Hematology

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