Nanogel-quantum dot complex for live cell imaging

Sayaka Toita, Urara Hasegawa, Kazunari Akiyoshi

Research output: Contribution to conferencePaperpeer-review

Abstract

Recently, we reported that nanogels of cholesterol-bearing pullulan (CHP) modified with amino groups(CHPNH2) acted as a novel carrier of quantum dots (QDs) for bioimaging. In this study, we investigated the formation of nanogel-QD complex and its potential application to live cell imaging. The size of the complex (304Qnm) varied depending on the types of proteins conjugated to QD. The complex nanopartides had little influence on cell function. The internalized QD into MSC were retained for 2 weeks. The results indicate that nanogel-QD complexes were versatile fluorescent probes for long-term cell imaging.

Original languageEnglish (US)
Pages4845
Number of pages1
StatePublished - 2006
Event55th Society of Polymer Science Japan Symposium on Macromolecules - Toyama, Japan
Duration: Sep 20 2006Sep 22 2006

Conference

Conference55th Society of Polymer Science Japan Symposium on Macromolecules
CountryJapan
CityToyama
Period9/20/069/22/06

All Science Journal Classification (ASJC) codes

  • Engineering(all)

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