Nanostructured microfluidic digestion system for rapid high-performance proteolysis

Gong Cheng, Si Jie Hao, Xu Yu, Siyang Zheng

Research output: Contribution to journalArticle

8 Citations (Scopus)

Abstract

A novel microfluidic protein digestion system with a nanostructured and bioactive inner surface was constructed by an easy biomimetic self-assembly strategy for rapid and effective proteolysis in 2 minutes, which is faster than the conventional overnight digestion methods. It is expected that this work would contribute to rapid online digestion in future high-throughput proteomics.

Original languageEnglish (US)
Pages (from-to)650-654
Number of pages5
JournalLab on a Chip
Volume15
Issue number3
DOIs
StatePublished - Feb 7 2015

Fingerprint

Proteolysis
Microfluidics
Biomimetics
Self assembly
Digestion
Throughput
Proteins
Proteomics

All Science Journal Classification (ASJC) codes

  • Bioengineering
  • Biochemistry
  • Chemistry(all)
  • Biomedical Engineering

Cite this

Cheng, Gong ; Hao, Si Jie ; Yu, Xu ; Zheng, Siyang. / Nanostructured microfluidic digestion system for rapid high-performance proteolysis. In: Lab on a Chip. 2015 ; Vol. 15, No. 3. pp. 650-654.
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Nanostructured microfluidic digestion system for rapid high-performance proteolysis. / Cheng, Gong; Hao, Si Jie; Yu, Xu; Zheng, Siyang.

In: Lab on a Chip, Vol. 15, No. 3, 07.02.2015, p. 650-654.

Research output: Contribution to journalArticle

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