Narcolepsy-Cataplexy: I. Clinical and Electrophysiologic Characteristics

Anthony Kales, Roger J. Cadieux, Constantin R. Soldatos, Edward O. Bixler, Paula K. Schweitzer, William T. Prey, Antonio Vela Bueno

Research output: Contribution to journalArticle

44 Citations (Scopus)

Abstract

The development, clinical course, and electrophysiologic characteristics of narcolepsy were evaluated in 50 adults who had a current complaint of sleep attacks and cataplexy. In most of the patients, the first symptoms, usually excessive daytime sleepiness and sleep attacks, developed during childhood or adolescence. The condition was invariably chronic. Patients frequently had family histories of some disorder of excessive daytime sleepiness. In nocturnal sleep or daytime nap recordings, all but three of the patients demonstrated a rapid-eyemovement (REM) period at sleep onset. Sleep apnea was found in only one patient. Our findings indicate that sleep laboratory recordings to detect a sleep-onset REM period are of little diagnostic value when the narcoleptic patient has cataplexy. Furthermore, narcoleptic patients require sleep laboratory evaluation for sleep apnea only when the presence of apnea is suggested by the sleep history.

Original languageEnglish (US)
Pages (from-to)164-168
Number of pages5
JournalArchives of Neurology
Volume39
Issue number3
DOIs
StatePublished - Mar 1982

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Cataplexy
Narcolepsy
Sleep
Sleep Apnea Syndromes
Apnea

All Science Journal Classification (ASJC) codes

  • Arts and Humanities (miscellaneous)
  • Clinical Neurology

Cite this

Kales, A., Cadieux, R. J., Soldatos, C. R., Bixler, E. O., Schweitzer, P. K., Prey, W. T., & Vela Bueno, A. (1982). Narcolepsy-Cataplexy: I. Clinical and Electrophysiologic Characteristics. Archives of Neurology, 39(3), 164-168. https://doi.org/10.1001/archneur.1982.00510150034008
Kales, Anthony ; Cadieux, Roger J. ; Soldatos, Constantin R. ; Bixler, Edward O. ; Schweitzer, Paula K. ; Prey, William T. ; Vela Bueno, Antonio. / Narcolepsy-Cataplexy : I. Clinical and Electrophysiologic Characteristics. In: Archives of Neurology. 1982 ; Vol. 39, No. 3. pp. 164-168.
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Kales, A, Cadieux, RJ, Soldatos, CR, Bixler, EO, Schweitzer, PK, Prey, WT & Vela Bueno, A 1982, 'Narcolepsy-Cataplexy: I. Clinical and Electrophysiologic Characteristics', Archives of Neurology, vol. 39, no. 3, pp. 164-168. https://doi.org/10.1001/archneur.1982.00510150034008

Narcolepsy-Cataplexy : I. Clinical and Electrophysiologic Characteristics. / Kales, Anthony; Cadieux, Roger J.; Soldatos, Constantin R.; Bixler, Edward O.; Schweitzer, Paula K.; Prey, William T.; Vela Bueno, Antonio.

In: Archives of Neurology, Vol. 39, No. 3, 03.1982, p. 164-168.

Research output: Contribution to journalArticle

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Kales A, Cadieux RJ, Soldatos CR, Bixler EO, Schweitzer PK, Prey WT et al. Narcolepsy-Cataplexy: I. Clinical and Electrophysiologic Characteristics. Archives of Neurology. 1982 Mar;39(3):164-168. https://doi.org/10.1001/archneur.1982.00510150034008