NASPGHAN Clinical Report on Postoperative Recurrence in Pediatric Crohn Disease

Judy B. Splawski, Marian D. Pffefferkorn, Marc E. Schaefer, Andrew S. Day, Oliver S. Soldes, Todd A. Ponsky, Philip Stein, Jess L. Kaplan, Shehzad A. Saeed

Research output: Contribution to journalArticle

7 Scopus citations

Abstract

Pediatric Crohn disease is characterized by clinical and endoscopic relapses. The inflammatory process is considered to be progressive and may lead to strictures, fistulas, and penetrating disease that may require surgery. In addition, medically refractory disease may be treated by surgical resection of inflamed bowel in an effort to reverse growth failure. The need for surgery in childhood suggests severe disease and these patients have an increased risk for recurrent disease and potentially more surgery. Data show that up to 55% of patients had clinical recurrence in the first 2 years after initial surgery. The current clinical report on postoperative recurrence in pediatric Crohn disease reviews the risk factors for early surgery and postoperative recurrence, operative risk factors for recurrence, and prevention and monitoring strategies for postoperative recurrence. We also propose an algorithm for postoperative management in pediatric Crohn disease.

Original languageEnglish (US)
Pages (from-to)475-486
Number of pages12
JournalJournal of pediatric gastroenterology and nutrition
Volume65
Issue number4
DOIs
StatePublished - Oct 1 2017

All Science Journal Classification (ASJC) codes

  • Pediatrics, Perinatology, and Child Health
  • Gastroenterology

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    Splawski, J. B., Pffefferkorn, M. D., Schaefer, M. E., Day, A. S., Soldes, O. S., Ponsky, T. A., Stein, P., Kaplan, J. L., & Saeed, S. A. (2017). NASPGHAN Clinical Report on Postoperative Recurrence in Pediatric Crohn Disease. Journal of pediatric gastroenterology and nutrition, 65(4), 475-486. https://doi.org/10.1097/MPG.0000000000001606