NCBI BLAST+ integrated into Galaxy

Peter J.A. Cock, John M. Chilton, Björn Grüning, James E. Johnson, Nicola Soranzo

Research output: Contribution to journalArticlepeer-review

61 Scopus citations

Abstract

Background: The NCBI BLAST suite has become ubiquitous in modern molecular biology and is used for small tasks such as checking capillary sequencing results of single PCR products, genome annotation or even larger scale pan-genome analyses. For early adopters of the Galaxy web-based biomedical data analysis platform, integrating BLAST into Galaxy was a natural step for sequence comparison workflows. Findings: The command line NCBI BLAST+ tool suite was wrapped for use within Galaxy. Appropriate datatypes were defined as needed. The integration of the BLAST+ tool suite into Galaxy has the goal of making common BLAST tasks easy and advanced tasks possible. Conclusions: This project is an informal international collaborative effort, and is deployed and used on Galaxy servers worldwide. Several examples of applications are described here.

Original languageEnglish (US)
Article number39
JournalGigaScience
Volume4
Issue number1
DOIs
StatePublished - 2015

All Science Journal Classification (ASJC) codes

  • Computer Science Applications
  • Health Informatics

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