Neonatal tolerance to K and D region alloantigen of H-2 complex: I-J region requirements

J. W. Streilein, J. Klein

Research output: Contribution to journalArticle

17 Scopus citations

Abstract

In this report, we analyze the relative abilities of individual H-2 allodeterminants to induce tolerance in comparison with the tolerogenic potential of conjoined disparities, including the entire H-2 segment. It was found that genes within the I region markedly influence the tolerogenicity of K and D region alloantigens and restrict the range and specificity of that tolerance in putatively tolerant animals.

Original languageEnglish (US)
Pages (from-to)732-735
Number of pages4
JournalTransplantation proceedings
Volume11
Issue number1
StatePublished - Jan 1 1979

All Science Journal Classification (ASJC) codes

  • Surgery
  • Transplantation

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