Neoterminal Ileal Polyposis and Ulceration after Restorative Proctocolectomy with a Current Review of the Literature

Venkata Subhash Gorrepati, Negar Rassaei, Kofi Clarke

Research output: Contribution to journalReview article

Abstract

After ileal pouch anal anastomosis, one of the frequently encountered complications is polyposis of the pouch. We describe a case of proximal neoterminal ileal polyposis associated with deep ulceration suggestive of Crohn's disease and review the available literature. A 36-year-old male presented with resistant pouchitis 11 years after surgery for ulcerative colitis. With all-negative initial workup, pouchoscopy showed multiple deep ulcers in the proximal ileum with some polyps. Biopsy of polyps showed inflammatory polyps with negative immunohistological staining for IgG pouchitis. With no treatable etiology for pouchitis and the presence of inflammatory polyps, there are no guidelines for surveillance of this condition. Definitive diagnosis is challenging and there is no consensus or recommended guidelines on the management.

Original languageEnglish (US)
Pages (from-to)158-164
Number of pages7
JournalCase Reports in Gastroenterology
Volume12
Issue number1
DOIs
StatePublished - Apr 13 2018

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Restorative Proctocolectomy
Pouchitis
Polyps
Guidelines
Colonic Pouches
Negative Staining
Ulcerative Colitis
Ileum
Crohn Disease
Ulcer
Immunoglobulin G
Biopsy

All Science Journal Classification (ASJC) codes

  • Gastroenterology

Cite this

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title = "Neoterminal Ileal Polyposis and Ulceration after Restorative Proctocolectomy with a Current Review of the Literature",
abstract = "After ileal pouch anal anastomosis, one of the frequently encountered complications is polyposis of the pouch. We describe a case of proximal neoterminal ileal polyposis associated with deep ulceration suggestive of Crohn's disease and review the available literature. A 36-year-old male presented with resistant pouchitis 11 years after surgery for ulcerative colitis. With all-negative initial workup, pouchoscopy showed multiple deep ulcers in the proximal ileum with some polyps. Biopsy of polyps showed inflammatory polyps with negative immunohistological staining for IgG pouchitis. With no treatable etiology for pouchitis and the presence of inflammatory polyps, there are no guidelines for surveillance of this condition. Definitive diagnosis is challenging and there is no consensus or recommended guidelines on the management.",
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Neoterminal Ileal Polyposis and Ulceration after Restorative Proctocolectomy with a Current Review of the Literature. / Gorrepati, Venkata Subhash; Rassaei, Negar; Clarke, Kofi.

In: Case Reports in Gastroenterology, Vol. 12, No. 1, 13.04.2018, p. 158-164.

Research output: Contribution to journalReview article

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