Neural substrates for head movements in humans: A functional magnetic resonance imaging study

Cecilia N. Prudente, Randall Stilla, Cathrin M. Buetefisch, Shivangi Singh, Ellen J. Hess, Xiaoping Hu, Krish Sathian, H. A. Jinnah

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

The neural systems controlling head movements are not well delineated in humans. It is not clear whether the ipsilateral or contralateral primary motor cortex is involved in turning the head right or left. Furthermore, the exact location of the neck motor area in the somatotopic organization of the motor homunculus is still debated and evidence for contributions from other brain regions in humans is scarce. Because currently available neuroimaging methods are not generally suitable for mapping brain activation patterns during head movements, we conducted fMRI scans during isometric tasks of the head. During isometric tasks, muscle contractions occur without an actual movement and they have been used to delineate patterns of brain activity related to movements of other body parts such as the hands. Healthy individuals were scanned during isometric head rotation or wrist extension. Isometric wrist extension was examined as a positive control and to establish the relative locations of head and hand regions in the motor cortex. Electromyographic recordings of neck and hand muscles during scanning ensured compliance with the tasks. Increased brain activity during isometric head rotation was observed bilaterally in the precentral gyrus, both medial and lateral to the hand area, as well the supplementary motor area, insula, putamen, and cerebellum. These findings clarify the location of the neck region in the motor homunculus and help to reconcile some of the conflicting results obtained in earlier studies.

Original languageEnglish (US)
Pages (from-to)9163-9172
Number of pages10
JournalJournal of Neuroscience
Volume35
Issue number24
DOIs
StatePublished - Jun 17 2015

Fingerprint

Head Movements
Motor Cortex
Head
Magnetic Resonance Imaging
Hand
Wrist
Brain
Neck
Brain Mapping
Neck Muscles
Putamen
Frontal Lobe
Muscle Contraction
Human Body
Neuroimaging
Cerebellum

All Science Journal Classification (ASJC) codes

  • Neuroscience(all)

Cite this

Prudente, C. N., Stilla, R., Buetefisch, C. M., Singh, S., Hess, E. J., Hu, X., ... Jinnah, H. A. (2015). Neural substrates for head movements in humans: A functional magnetic resonance imaging study. Journal of Neuroscience, 35(24), 9163-9172. https://doi.org/10.1523/JNEUROSCI.0851-15.2015
Prudente, Cecilia N. ; Stilla, Randall ; Buetefisch, Cathrin M. ; Singh, Shivangi ; Hess, Ellen J. ; Hu, Xiaoping ; Sathian, Krish ; Jinnah, H. A. / Neural substrates for head movements in humans : A functional magnetic resonance imaging study. In: Journal of Neuroscience. 2015 ; Vol. 35, No. 24. pp. 9163-9172.
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Prudente, CN, Stilla, R, Buetefisch, CM, Singh, S, Hess, EJ, Hu, X, Sathian, K & Jinnah, HA 2015, 'Neural substrates for head movements in humans: A functional magnetic resonance imaging study', Journal of Neuroscience, vol. 35, no. 24, pp. 9163-9172. https://doi.org/10.1523/JNEUROSCI.0851-15.2015

Neural substrates for head movements in humans : A functional magnetic resonance imaging study. / Prudente, Cecilia N.; Stilla, Randall; Buetefisch, Cathrin M.; Singh, Shivangi; Hess, Ellen J.; Hu, Xiaoping; Sathian, Krish; Jinnah, H. A.

In: Journal of Neuroscience, Vol. 35, No. 24, 17.06.2015, p. 9163-9172.

Research output: Contribution to journalArticle

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