Neuroendocrine, Psychophysiological and Subjective Reactivity to an Alcohol Placebo in Male Alcoholic Patients

Zelig S. Dolinsky, David E. Morse, Richard F. Kaplan, Roger E. Meyer, Douglas Corry, Ovide F. Pomerleau

Research output: Contribution to journalArticlepeer-review

14 Scopus citations

Abstract

Alteration in neuroendocrine activity associated with the regulation of energy metabolism and food intake may play a role in characterizing the alcohol dependent state. Alcoholics, when compared to controls, demonstrated significantly larger and more rapid glucose and insulin responses following the consumption of a placebo beer, which they believed contained alcohol. The existence of significant correlations between peak neuroendocrine responses and desire to drink, anxiety, as well as psychophysiological responses in alcoholics suggests the potential multivariate nature of the biological/behavioral state associated with alcohol dependence.

Original languageEnglish (US)
Pages (from-to)296-300
Number of pages5
JournalAlcoholism: Clinical and Experimental Research
Volume11
Issue number3
DOIs
StatePublished - Jun 1987

All Science Journal Classification (ASJC) codes

  • Medicine (miscellaneous)
  • Toxicology
  • Psychiatry and Mental health

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