Neuroleukemiosis: Case report of leukemic nerve infiltration in acute lymphoblastic leukemia

Dawit G. Aregawi, Jonathan H. Sherman, Michael G. Douvas, Ted M. Burns, David Schiff

Research output: Contribution to journalArticlepeer-review

29 Scopus citations


We describe a patient in remission from acute lymphoblastic leukemia who developed a painless common peroneal neuropathy. Magnetic resonance imaging (MRI) revealed nerve thickening and enhancement, while a positron emission tomography (PET) scan demonstrated increased fluorodeoxyglucose uptake in a large segment of the neurovascular bundle, suggesting peripheral nerve infiltration. Both findings resolved following treatment with chemotherapy that crossed the blood-nerve barrier. In selected patients presenting with peripheral neuropathy, MRI and PET scan can be helpful in the diagnosis of peripheral nerve infiltration.

Original languageEnglish (US)
Pages (from-to)1196-1200
Number of pages5
JournalMuscle and Nerve
Issue number3
StatePublished - Sep 2008

All Science Journal Classification (ASJC) codes

  • Physiology
  • Clinical Neurology
  • Cellular and Molecular Neuroscience
  • Physiology (medical)


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