New insights into the pathophysiology of diabetic retinopathy: Potential cell-specific therapeutic targets

T. W. Gardner, D. A. Antonetti, A. J. Barber, K. F. LaNoue, M. Nakamura

Research output: Contribution to journalReview articlepeer-review

55 Scopus citations

Abstract

Diabetic retinopathy, a leading cause of vision impairment, is classically defined by its vascular lesions. This review examines how diabetes affects vascular cells, as well as neurons, macroglia, and microglia. The cellular and clinical elements of diabetic retinopathy have many features of chronic inflammation. Understanding the individual cell-specific and global inflammatory changes in the retina may lead to novel therapeutic approaches to prevent vision loss.

Original languageEnglish (US)
Pages (from-to)601-608
Number of pages8
JournalDiabetes Technology and Therapeutics
Volume2
Issue number4
DOIs
StatePublished - 2000

All Science Journal Classification (ASJC) codes

  • Endocrinology, Diabetes and Metabolism
  • Endocrinology
  • Medical Laboratory Technology

Fingerprint Dive into the research topics of 'New insights into the pathophysiology of diabetic retinopathy: Potential cell-specific therapeutic targets'. Together they form a unique fingerprint.

Cite this