A reinvestigation of Jaspis splendans afforded the novel compounds jaspamide D-G plus the known compounds jaspamide and jaspamides B and C. All compounds exhibited potent cytotoxic activities and were shown to cause microfilament disruption. Biological activity and structural elucidation are reported here.
|Original language||English (US)|
|Number of pages||8|
|State||Published - Jun 11 2007|
All Science Journal Classification (ASJC) codes
- Drug Discovery
- Organic Chemistry