NK cell receptors in antiviral immunity

Janice M. Moser, Anthony M. Byers, Aron E. Lukacher

Research output: Contribution to journalReview article

32 Scopus citations

Abstract

An array of inhibitory and activating receptors initially identified on NK cells are also expressed by conventional CD8+ αβ T cells. New evidence strongly implicates these 'NK cell receptors' in modulating NK cell and virus-specific CD8+ T cell responses against a variety of viral infections. Precise regulation of NK cell and T cell responses by these receptors optimizes antiviral immunity while preventing immunological bystander pathology and autoimmunity.

Original languageEnglish (US)
Pages (from-to)509-516
Number of pages8
JournalCurrent Opinion in Immunology
Volume14
Issue number4
DOIs
StatePublished - Aug 1 2002

All Science Journal Classification (ASJC) codes

  • Immunology and Allergy
  • Immunology

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