No evidence for intra-segment recombination of 2009 H1N1 influenza virus in swine

Maciej F. Boni, Gavin J.D. Smith, Edward C. Holmes, Dhanasekaran Vijaykrishna

Research output: Contribution to journalLetter

9 Citations (Scopus)

Abstract

Hao (2011) reported that the PB2 genes of three swine influenza A viruses were likely generated through homologous recombination between two closely related parental strains. However, we show that Hao's observation is an artifact of incorrect taxon sampling arising through the lack of an appropriate evolutionary context. Through rigorous phylogenetic analyses we explain the evolutionary origins of these stains and confirm the lack of any statistical support for intra-segmental recombination.

Original languageEnglish (US)
Pages (from-to)242-245
Number of pages4
JournalGene
Volume494
Issue number2
DOIs
StatePublished - Feb 25 2012

Fingerprint

H1N1 Subtype Influenza A Virus
Homologous Recombination
Influenza A virus
Orthomyxoviridae
Artifacts
Genetic Recombination
Coloring Agents
Swine
Observation
Genes

All Science Journal Classification (ASJC) codes

  • Genetics

Cite this

Boni, Maciej F. ; Smith, Gavin J.D. ; Holmes, Edward C. ; Vijaykrishna, Dhanasekaran. / No evidence for intra-segment recombination of 2009 H1N1 influenza virus in swine. In: Gene. 2012 ; Vol. 494, No. 2. pp. 242-245.
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No evidence for intra-segment recombination of 2009 H1N1 influenza virus in swine. / Boni, Maciej F.; Smith, Gavin J.D.; Holmes, Edward C.; Vijaykrishna, Dhanasekaran.

In: Gene, Vol. 494, No. 2, 25.02.2012, p. 242-245.

Research output: Contribution to journalLetter

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