Nocturnal sleep and blood pressure in essential hypertension

Edward Bixler, Anthony Kales, Antonio Vela-Bueno, Douglas E. Niklaus, Duane D. Shubert, Constantin R. Soldatos

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

Blood pressure and sleep-wakefulness patterns were monitored in the sleep laboratory over four consecutive nights in six patients with mild hypertension and six age- and sex-matched controls. In both hypertensives and normals, blood pressure levels decreased during sleep compared with presleep levels by 16.6 and 8.4% respectively; levels for hypertensives, however, remained significantly above those for the normals. The nocturnal drop in blood pressure for both groups appeared to be related primarily to the general state of sleep rather than to any specific sleep stage. Nocturnal patterns of sleep stages and sleep cycling were almost identical for the two groups. Nocturnal blood pressure fluctuation was correlated positively with the distribution of noeturnal wakefulness in hypertensives but not in normotensives. This suggests that with hypertension there is some diminution of the dampening effect of sleep itself upon blood pressure which normally carries over into periods of nocturnal wakefulness. This alteration in patients with mild hypertension may reflect a decrease in the sensitivity of the baroreceptor reflex or some other pathophysiological process.

Original languageEnglish (US)
Pages (from-to)1-11
Number of pages11
JournalInternational Journal of Neuroscience
Volume40
Issue number1-2
DOIs
StatePublished - Jan 1 1988

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Sleep
Blood Pressure
Wakefulness
Sleep Stages
Hypertension
Baroreflex
Essential Hypertension

All Science Journal Classification (ASJC) codes

  • Neuroscience(all)

Cite this

Bixler, E., Kales, A., Vela-Bueno, A., Niklaus, D. E., Shubert, D. D., & Soldatos, C. R. (1988). Nocturnal sleep and blood pressure in essential hypertension. International Journal of Neuroscience, 40(1-2), 1-11. https://doi.org/10.3109/00207458808985721
Bixler, Edward ; Kales, Anthony ; Vela-Bueno, Antonio ; Niklaus, Douglas E. ; Shubert, Duane D. ; Soldatos, Constantin R. / Nocturnal sleep and blood pressure in essential hypertension. In: International Journal of Neuroscience. 1988 ; Vol. 40, No. 1-2. pp. 1-11.
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Bixler, E, Kales, A, Vela-Bueno, A, Niklaus, DE, Shubert, DD & Soldatos, CR 1988, 'Nocturnal sleep and blood pressure in essential hypertension', International Journal of Neuroscience, vol. 40, no. 1-2, pp. 1-11. https://doi.org/10.3109/00207458808985721

Nocturnal sleep and blood pressure in essential hypertension. / Bixler, Edward; Kales, Anthony; Vela-Bueno, Antonio; Niklaus, Douglas E.; Shubert, Duane D.; Soldatos, Constantin R.

In: International Journal of Neuroscience, Vol. 40, No. 1-2, 01.01.1988, p. 1-11.

Research output: Contribution to journalArticle

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Bixler E, Kales A, Vela-Bueno A, Niklaus DE, Shubert DD, Soldatos CR. Nocturnal sleep and blood pressure in essential hypertension. International Journal of Neuroscience. 1988 Jan 1;40(1-2):1-11. https://doi.org/10.3109/00207458808985721