NOE difference spectroscopy of some 5‐substituted and 5,5‐disubstituted hydantoins

Michael De Rosa, Alan J. Freyer

Research output: Contribution to journalLetter

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The nOe difference (NOED) spectra of twelve 5‐substituted‐ and 5,5‐disubstituted hydantoins were recorded in deuteriochloroform. The nOe's observed from the interaction of substituents on C‐5 with the proton on N‐1 are more reliable than the chemical shift of the N‐1 proton for structure determination.

Original languageEnglish (US)
Pages (from-to)1661-1663
Number of pages3
JournalJournal of Heterocyclic Chemistry
Issue number5
Publication statusPublished - Jan 1 1995


All Science Journal Classification (ASJC) codes

  • Organic Chemistry

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