Non-faradaic impedance characterization of an evaporating droplet for microfluidic and biosensing applications

Piyush Dak; Aida Ebrahimi; Muhammad A. Alam

doi:10.1039/c4lc00193a

Non-faradaic impedance characterization of an evaporating droplet for microfluidic and biosensing applications

Piyush Dak, Aida Ebrahimi, Muhammad A. Alam

Electrical Engineering

Research output: Contribution to journal › Article › peer-review

21 Scopus citations

Abstract

We have developed a general numerical/analytical theory of non-faradaic impedance of an evaporating droplet, and validated the model by experiments involving droplets of various analyte concentrations deposited on a surface defined by coplanar electrodes. The impedance of the droplet Z(n ₀,t,f) is analyzed as a function of the concentration (n₀) of the ions in the solution, the measurement frequency (f) and the evaporation time (t). We illustrate the versatility of the model by determining the sensitivity enhancement α(t) of the droplet-based impedimetric nano-biosensor under different regimes of operation. The model should have broad applications in the characterization/optimization of droplet-based systems, especially lab-on-chip components involving digital microfluidics. This journal is

Original language	English (US)
Pages (from-to)	2469-2479
Number of pages	11
Journal	Lab on a Chip
Volume	14
Issue number	14
DOIs	https://doi.org/10.1039/c4lc00193a
State	Published - Jul 21 2014

All Science Journal Classification (ASJC) codes

Bioengineering
Biochemistry
Chemistry(all)
Biomedical Engineering

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10.1039/c4lc00193a

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