Abstract
We have developed a general numerical/analytical theory of non-faradaic impedance of an evaporating droplet, and validated the model by experiments involving droplets of various analyte concentrations deposited on a surface defined by coplanar electrodes. The impedance of the droplet Z(n 0,t,f) is analyzed as a function of the concentration (n0) of the ions in the solution, the measurement frequency (f) and the evaporation time (t). We illustrate the versatility of the model by determining the sensitivity enhancement α(t) of the droplet-based impedimetric nano-biosensor under different regimes of operation. The model should have broad applications in the characterization/optimization of droplet-based systems, especially lab-on-chip components involving digital microfluidics. This journal is
Original language | English (US) |
---|---|
Pages (from-to) | 2469-2479 |
Number of pages | 11 |
Journal | Lab on a Chip |
Volume | 14 |
Issue number | 14 |
DOIs | |
State | Published - Jul 21 2014 |
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All Science Journal Classification (ASJC) codes
- Bioengineering
- Biochemistry
- Chemistry(all)
- Biomedical Engineering
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Non-faradaic impedance characterization of an evaporating droplet for microfluidic and biosensing applications. / Dak, Piyush; Ebrahimi, Aida; Alam, Muhammad A.
In: Lab on a Chip, Vol. 14, No. 14, 21.07.2014, p. 2469-2479.Research output: Contribution to journal › Article
TY - JOUR
T1 - Non-faradaic impedance characterization of an evaporating droplet for microfluidic and biosensing applications
AU - Dak, Piyush
AU - Ebrahimi, Aida
AU - Alam, Muhammad A.
PY - 2014/7/21
Y1 - 2014/7/21
N2 - We have developed a general numerical/analytical theory of non-faradaic impedance of an evaporating droplet, and validated the model by experiments involving droplets of various analyte concentrations deposited on a surface defined by coplanar electrodes. The impedance of the droplet Z(n 0,t,f) is analyzed as a function of the concentration (n0) of the ions in the solution, the measurement frequency (f) and the evaporation time (t). We illustrate the versatility of the model by determining the sensitivity enhancement α(t) of the droplet-based impedimetric nano-biosensor under different regimes of operation. The model should have broad applications in the characterization/optimization of droplet-based systems, especially lab-on-chip components involving digital microfluidics. This journal is
AB - We have developed a general numerical/analytical theory of non-faradaic impedance of an evaporating droplet, and validated the model by experiments involving droplets of various analyte concentrations deposited on a surface defined by coplanar electrodes. The impedance of the droplet Z(n 0,t,f) is analyzed as a function of the concentration (n0) of the ions in the solution, the measurement frequency (f) and the evaporation time (t). We illustrate the versatility of the model by determining the sensitivity enhancement α(t) of the droplet-based impedimetric nano-biosensor under different regimes of operation. The model should have broad applications in the characterization/optimization of droplet-based systems, especially lab-on-chip components involving digital microfluidics. This journal is
UR - http://www.scopus.com/inward/record.url?scp=84902477242&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84902477242&partnerID=8YFLogxK
U2 - 10.1039/c4lc00193a
DO - 10.1039/c4lc00193a
M3 - Article
C2 - 24850073
AN - SCOPUS:84902477242
VL - 14
SP - 2469
EP - 2479
JO - Lab on a Chip - Miniaturisation for Chemistry and Biology
JF - Lab on a Chip - Miniaturisation for Chemistry and Biology
SN - 1473-0197
IS - 14
ER -