Non-Graft-versus-Host Disease Ocular Complications after Hematopoietic Cell Transplantation: Expert Review from the Late Effects and Quality of Life Working Committee of the Center for International Blood and Marrow Transplant Research and the Transplant Complications Working Party of the European Society for Blood and Marrow Transplantation

Yoshihiro Inamoto, Igor Petriček, Linda Burns, Saurabh Chhabra, Zachariah DeFilipp, Peiman Hematti, Alicia Rovó, Raquel Schears, Ami Shah, Vaibhav Agrawal, Aisha Ahmed, Ibrahim Ahmed, Asim Ali, Mahmoud Aljurf, Hassan Alkhateeb, Amer Beitinjaneh, Neel Bhatt, Dave Buchbinder, Michael Byrne, Natalie CallanderKristina Fahnehjelm, Nosha Farhadfar, Robert Peter Gale, Siddhartha Ganguly, Shahrukh Hashmi, Gerhard C. Hildebrandt, Erich Horn, Ann Jakubowski, Rammurti T. Kamble, Jason Law, Catherine Lee, Sunita Nathan, Olaf Penack, Ravi Pingali, Pinki Prasad, Drazen Pulanic, Seth Rotz, Aditya Shreenivas, Amir Steinberg, Khalid Tabbara, André Tichelli, Baldeep Wirk, Jean Yared, Grzegorz W. Basak, Minoo Battiwalla, Rafael Duarte, Bipin N. Savani, Mary E.D. Flowers, Bronwen E. Shaw, Nuria Valdés-Sanz

Research output: Contribution to journalReview article

3 Citations (Scopus)

Abstract

Non-graft-versus-host disease (GVHD)ocular complications are generally uncommon after hematopoietic cell transplantation (HCT)but can cause prolonged morbidity affecting activities of daily living and quality of life. Here we provide an expert review of non-GVHD ocular complications in a collaboration between transplantation physicians and ophthalmologists through the Late Effects and Quality of Life Working Committee of the Center for International Blood and Marrow Transplant Research and the Transplant Complications Working Party of the European Society of Blood and Marrow Transplantation. Complications discussed in this review include cataracts, glaucoma, ocular infections, ocular involvement with malignancy, ischemic microvascular retinopathy, central retinal vein occlusion, retinal hemorrhage, retinal detachment and ocular toxicities associated with medications. We summarize the incidence, risk factors, screening, prevention, and treatment of individual complications and generate evidence-based recommendations. Baseline ocular evaluation before HCT should be considered in all patients who undergo HCT. Follow-up evaluations should be considered according to clinical signs and symptoms and risk factors. Better preventive strategies and treatments remain to be investigated for individual ocular complications after HCT. Both transplantation physicians and ophthalmologists should be knowledgeable about non-GVHD ocular complications and provide comprehensive collaborative team care.

Original languageEnglish (US)
Pages (from-to)e145-e154
JournalBiology of Blood and Marrow Transplantation
Volume25
Issue number5
DOIs
StatePublished - May 2019

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Cell Transplantation
Transplantation
Bone Marrow
Quality of Life
Transplants
Research
Retinal Hemorrhage
Physicians
Eye Infections
Retinal Vein
Retinal Vein Occlusion
Retinal Detachment
Activities of Daily Living
Glaucoma
Cataract
Signs and Symptoms
Morbidity
Incidence
Therapeutics
Neoplasms

All Science Journal Classification (ASJC) codes

  • Hematology
  • Transplantation

Cite this

Inamoto, Yoshihiro ; Petriček, Igor ; Burns, Linda ; Chhabra, Saurabh ; DeFilipp, Zachariah ; Hematti, Peiman ; Rovó, Alicia ; Schears, Raquel ; Shah, Ami ; Agrawal, Vaibhav ; Ahmed, Aisha ; Ahmed, Ibrahim ; Ali, Asim ; Aljurf, Mahmoud ; Alkhateeb, Hassan ; Beitinjaneh, Amer ; Bhatt, Neel ; Buchbinder, Dave ; Byrne, Michael ; Callander, Natalie ; Fahnehjelm, Kristina ; Farhadfar, Nosha ; Gale, Robert Peter ; Ganguly, Siddhartha ; Hashmi, Shahrukh ; Hildebrandt, Gerhard C. ; Horn, Erich ; Jakubowski, Ann ; Kamble, Rammurti T. ; Law, Jason ; Lee, Catherine ; Nathan, Sunita ; Penack, Olaf ; Pingali, Ravi ; Prasad, Pinki ; Pulanic, Drazen ; Rotz, Seth ; Shreenivas, Aditya ; Steinberg, Amir ; Tabbara, Khalid ; Tichelli, André ; Wirk, Baldeep ; Yared, Jean ; Basak, Grzegorz W. ; Battiwalla, Minoo ; Duarte, Rafael ; Savani, Bipin N. ; Flowers, Mary E.D. ; Shaw, Bronwen E. ; Valdés-Sanz, Nuria. / Non-Graft-versus-Host Disease Ocular Complications after Hematopoietic Cell Transplantation : Expert Review from the Late Effects and Quality of Life Working Committee of the Center for International Blood and Marrow Transplant Research and the Transplant Complications Working Party of the European Society for Blood and Marrow Transplantation. In: Biology of Blood and Marrow Transplantation. 2019 ; Vol. 25, No. 5. pp. e145-e154.
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title = "Non-Graft-versus-Host Disease Ocular Complications after Hematopoietic Cell Transplantation: Expert Review from the Late Effects and Quality of Life Working Committee of the Center for International Blood and Marrow Transplant Research and the Transplant Complications Working Party of the European Society for Blood and Marrow Transplantation",
abstract = "Non-graft-versus-host disease (GVHD)ocular complications are generally uncommon after hematopoietic cell transplantation (HCT)but can cause prolonged morbidity affecting activities of daily living and quality of life. Here we provide an expert review of non-GVHD ocular complications in a collaboration between transplantation physicians and ophthalmologists through the Late Effects and Quality of Life Working Committee of the Center for International Blood and Marrow Transplant Research and the Transplant Complications Working Party of the European Society of Blood and Marrow Transplantation. Complications discussed in this review include cataracts, glaucoma, ocular infections, ocular involvement with malignancy, ischemic microvascular retinopathy, central retinal vein occlusion, retinal hemorrhage, retinal detachment and ocular toxicities associated with medications. We summarize the incidence, risk factors, screening, prevention, and treatment of individual complications and generate evidence-based recommendations. Baseline ocular evaluation before HCT should be considered in all patients who undergo HCT. Follow-up evaluations should be considered according to clinical signs and symptoms and risk factors. Better preventive strategies and treatments remain to be investigated for individual ocular complications after HCT. Both transplantation physicians and ophthalmologists should be knowledgeable about non-GVHD ocular complications and provide comprehensive collaborative team care.",
author = "Yoshihiro Inamoto and Igor Petriček and Linda Burns and Saurabh Chhabra and Zachariah DeFilipp and Peiman Hematti and Alicia Rov{\'o} and Raquel Schears and Ami Shah and Vaibhav Agrawal and Aisha Ahmed and Ibrahim Ahmed and Asim Ali and Mahmoud Aljurf and Hassan Alkhateeb and Amer Beitinjaneh and Neel Bhatt and Dave Buchbinder and Michael Byrne and Natalie Callander and Kristina Fahnehjelm and Nosha Farhadfar and Gale, {Robert Peter} and Siddhartha Ganguly and Shahrukh Hashmi and Hildebrandt, {Gerhard C.} and Erich Horn and Ann Jakubowski and Kamble, {Rammurti T.} and Jason Law and Catherine Lee and Sunita Nathan and Olaf Penack and Ravi Pingali and Pinki Prasad and Drazen Pulanic and Seth Rotz and Aditya Shreenivas and Amir Steinberg and Khalid Tabbara and Andr{\'e} Tichelli and Baldeep Wirk and Jean Yared and Basak, {Grzegorz W.} and Minoo Battiwalla and Rafael Duarte and Savani, {Bipin N.} and Flowers, {Mary E.D.} and Shaw, {Bronwen E.} and Nuria Vald{\'e}s-Sanz",
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Inamoto, Y, Petriček, I, Burns, L, Chhabra, S, DeFilipp, Z, Hematti, P, Rovó, A, Schears, R, Shah, A, Agrawal, V, Ahmed, A, Ahmed, I, Ali, A, Aljurf, M, Alkhateeb, H, Beitinjaneh, A, Bhatt, N, Buchbinder, D, Byrne, M, Callander, N, Fahnehjelm, K, Farhadfar, N, Gale, RP, Ganguly, S, Hashmi, S, Hildebrandt, GC, Horn, E, Jakubowski, A, Kamble, RT, Law, J, Lee, C, Nathan, S, Penack, O, Pingali, R, Prasad, P, Pulanic, D, Rotz, S, Shreenivas, A, Steinberg, A, Tabbara, K, Tichelli, A, Wirk, B, Yared, J, Basak, GW, Battiwalla, M, Duarte, R, Savani, BN, Flowers, MED, Shaw, BE & Valdés-Sanz, N 2019, 'Non-Graft-versus-Host Disease Ocular Complications after Hematopoietic Cell Transplantation: Expert Review from the Late Effects and Quality of Life Working Committee of the Center for International Blood and Marrow Transplant Research and the Transplant Complications Working Party of the European Society for Blood and Marrow Transplantation', Biology of Blood and Marrow Transplantation, vol. 25, no. 5, pp. e145-e154. https://doi.org/10.1016/j.bbmt.2018.11.033

Non-Graft-versus-Host Disease Ocular Complications after Hematopoietic Cell Transplantation : Expert Review from the Late Effects and Quality of Life Working Committee of the Center for International Blood and Marrow Transplant Research and the Transplant Complications Working Party of the European Society for Blood and Marrow Transplantation. / Inamoto, Yoshihiro; Petriček, Igor; Burns, Linda; Chhabra, Saurabh; DeFilipp, Zachariah; Hematti, Peiman; Rovó, Alicia; Schears, Raquel; Shah, Ami; Agrawal, Vaibhav; Ahmed, Aisha; Ahmed, Ibrahim; Ali, Asim; Aljurf, Mahmoud; Alkhateeb, Hassan; Beitinjaneh, Amer; Bhatt, Neel; Buchbinder, Dave; Byrne, Michael; Callander, Natalie; Fahnehjelm, Kristina; Farhadfar, Nosha; Gale, Robert Peter; Ganguly, Siddhartha; Hashmi, Shahrukh; Hildebrandt, Gerhard C.; Horn, Erich; Jakubowski, Ann; Kamble, Rammurti T.; Law, Jason; Lee, Catherine; Nathan, Sunita; Penack, Olaf; Pingali, Ravi; Prasad, Pinki; Pulanic, Drazen; Rotz, Seth; Shreenivas, Aditya; Steinberg, Amir; Tabbara, Khalid; Tichelli, André; Wirk, Baldeep; Yared, Jean; Basak, Grzegorz W.; Battiwalla, Minoo; Duarte, Rafael; Savani, Bipin N.; Flowers, Mary E.D.; Shaw, Bronwen E.; Valdés-Sanz, Nuria.

In: Biology of Blood and Marrow Transplantation, Vol. 25, No. 5, 05.2019, p. e145-e154.

Research output: Contribution to journalReview article

TY - JOUR

T1 - Non-Graft-versus-Host Disease Ocular Complications after Hematopoietic Cell Transplantation

T2 - Expert Review from the Late Effects and Quality of Life Working Committee of the Center for International Blood and Marrow Transplant Research and the Transplant Complications Working Party of the European Society for Blood and Marrow Transplantation

AU - Inamoto, Yoshihiro

AU - Petriček, Igor

AU - Burns, Linda

AU - Chhabra, Saurabh

AU - DeFilipp, Zachariah

AU - Hematti, Peiman

AU - Rovó, Alicia

AU - Schears, Raquel

AU - Shah, Ami

AU - Agrawal, Vaibhav

AU - Ahmed, Aisha

AU - Ahmed, Ibrahim

AU - Ali, Asim

AU - Aljurf, Mahmoud

AU - Alkhateeb, Hassan

AU - Beitinjaneh, Amer

AU - Bhatt, Neel

AU - Buchbinder, Dave

AU - Byrne, Michael

AU - Callander, Natalie

AU - Fahnehjelm, Kristina

AU - Farhadfar, Nosha

AU - Gale, Robert Peter

AU - Ganguly, Siddhartha

AU - Hashmi, Shahrukh

AU - Hildebrandt, Gerhard C.

AU - Horn, Erich

AU - Jakubowski, Ann

AU - Kamble, Rammurti T.

AU - Law, Jason

AU - Lee, Catherine

AU - Nathan, Sunita

AU - Penack, Olaf

AU - Pingali, Ravi

AU - Prasad, Pinki

AU - Pulanic, Drazen

AU - Rotz, Seth

AU - Shreenivas, Aditya

AU - Steinberg, Amir

AU - Tabbara, Khalid

AU - Tichelli, André

AU - Wirk, Baldeep

AU - Yared, Jean

AU - Basak, Grzegorz W.

AU - Battiwalla, Minoo

AU - Duarte, Rafael

AU - Savani, Bipin N.

AU - Flowers, Mary E.D.

AU - Shaw, Bronwen E.

AU - Valdés-Sanz, Nuria

PY - 2019/5

Y1 - 2019/5

N2 - Non-graft-versus-host disease (GVHD)ocular complications are generally uncommon after hematopoietic cell transplantation (HCT)but can cause prolonged morbidity affecting activities of daily living and quality of life. Here we provide an expert review of non-GVHD ocular complications in a collaboration between transplantation physicians and ophthalmologists through the Late Effects and Quality of Life Working Committee of the Center for International Blood and Marrow Transplant Research and the Transplant Complications Working Party of the European Society of Blood and Marrow Transplantation. Complications discussed in this review include cataracts, glaucoma, ocular infections, ocular involvement with malignancy, ischemic microvascular retinopathy, central retinal vein occlusion, retinal hemorrhage, retinal detachment and ocular toxicities associated with medications. We summarize the incidence, risk factors, screening, prevention, and treatment of individual complications and generate evidence-based recommendations. Baseline ocular evaluation before HCT should be considered in all patients who undergo HCT. Follow-up evaluations should be considered according to clinical signs and symptoms and risk factors. Better preventive strategies and treatments remain to be investigated for individual ocular complications after HCT. Both transplantation physicians and ophthalmologists should be knowledgeable about non-GVHD ocular complications and provide comprehensive collaborative team care.

AB - Non-graft-versus-host disease (GVHD)ocular complications are generally uncommon after hematopoietic cell transplantation (HCT)but can cause prolonged morbidity affecting activities of daily living and quality of life. Here we provide an expert review of non-GVHD ocular complications in a collaboration between transplantation physicians and ophthalmologists through the Late Effects and Quality of Life Working Committee of the Center for International Blood and Marrow Transplant Research and the Transplant Complications Working Party of the European Society of Blood and Marrow Transplantation. Complications discussed in this review include cataracts, glaucoma, ocular infections, ocular involvement with malignancy, ischemic microvascular retinopathy, central retinal vein occlusion, retinal hemorrhage, retinal detachment and ocular toxicities associated with medications. We summarize the incidence, risk factors, screening, prevention, and treatment of individual complications and generate evidence-based recommendations. Baseline ocular evaluation before HCT should be considered in all patients who undergo HCT. Follow-up evaluations should be considered according to clinical signs and symptoms and risk factors. Better preventive strategies and treatments remain to be investigated for individual ocular complications after HCT. Both transplantation physicians and ophthalmologists should be knowledgeable about non-GVHD ocular complications and provide comprehensive collaborative team care.

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