Noninvasive ultrasonic transdermal insulin delivery in rabbits using the light weight cymbal array

Seungjun Lee, Benjamin Snyder, Richard Joseph Meyer, Jr., Vivekanand Nayak, Douglas Markley, Robert E. Newnham, Nadine Barrie Smith

Research output: Contribution to journalConference articlepeer-review

1 Scopus citations

Abstract

The low profile Cymbal array for enhanced insulin transport through in vivo animal skin using rabbits was discussed. Through the use of the cymbal array, the US-insulin experimental group showed a blood glucose level decrease of -208.1 ± 29 mg/dL within 90 minutes. The small increase in blood glucose was attributable to the low skin permeability of insulin. It was shown that the US alone did not alter the blood glucose level of the rabbit.

Original languageEnglish (US)
Pages (from-to)736-739
Number of pages4
JournalProceedings of the IEEE Ultrasonics Symposium
Volume1
StatePublished - Dec 1 2003
Event2003 IEEE Ultrasonics Symposium - Proceedings - Honolulu, HI, United States
Duration: Oct 5 2003Oct 8 2003

All Science Journal Classification (ASJC) codes

  • Acoustics and Ultrasonics

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