Novel adaptive control system for ultrasound hyperthermia treatment of prostate disease

L. Sun, Jeffrey Louis Schiano, N. B. Smith

    Research output: Contribution to journalArticle

    4 Citations (Scopus)

    Abstract

    A novel model reference adaptive control (MRAC) method was proposed and tested with a transrectal intracavitary applicator for thermal treatment of prostate disease using ultrasound hyperthermia. Two significant advantages of this innovative adaptive control method are: 1) there is no need of a priori knowledge of the tissue properties and 2) the controller could adaptively change the amplitudes and phases of the array's driving signal according to the perfusion rate and other dynamic tissue properties. Computer simulations, ex vivo and in vivo experimental results all showed that with this adaptive controller the tissue was heated up to 43 ± 0.2°C within 7 ± 2 minutes, and adaptively maintained 43°C with dynamic blood flow for the rest period of the hyperthermia.

    Original languageEnglish (US)
    Pages (from-to)1274-1277
    Number of pages4
    JournalProceedings of the IEEE Ultrasonics Symposium
    Volume2
    StatePublished - 2003

    Fingerprint

    Adaptive control systems
    adaptive control
    hyperthermia
    Ultrasonics
    Tissue
    controllers
    model reference adaptive control
    Model reference adaptive control
    Controllers
    Applicators
    blood flow
    Blood
    computerized simulation
    Heat treatment
    Computer simulation

    All Science Journal Classification (ASJC) codes

    • Engineering(all)

    Cite this

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    abstract = "A novel model reference adaptive control (MRAC) method was proposed and tested with a transrectal intracavitary applicator for thermal treatment of prostate disease using ultrasound hyperthermia. Two significant advantages of this innovative adaptive control method are: 1) there is no need of a priori knowledge of the tissue properties and 2) the controller could adaptively change the amplitudes and phases of the array's driving signal according to the perfusion rate and other dynamic tissue properties. Computer simulations, ex vivo and in vivo experimental results all showed that with this adaptive controller the tissue was heated up to 43 ± 0.2°C within 7 ± 2 minutes, and adaptively maintained 43°C with dynamic blood flow for the rest period of the hyperthermia.",
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    Novel adaptive control system for ultrasound hyperthermia treatment of prostate disease. / Sun, L.; Schiano, Jeffrey Louis; Smith, N. B.

    In: Proceedings of the IEEE Ultrasonics Symposium, Vol. 2, 2003, p. 1274-1277.

    Research output: Contribution to journalArticle

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