Novel Applications of Urethane/Urea Chemistry in the Field of Biomaterials

G. B. Kim, J. Guo, J. Hu, D. Shan, Jian Yang

Research output: Chapter in Book/Report/Conference proceedingChapter

1 Citation (Scopus)

Abstract

Polyurethanes have been widely used as biomaterials since the 1960s due to their wide range of tunable physical, chemical, mechanical, biological, and medical properties. They have been used in building various applications including pacemaker lead insulation, artificial veins and arteries, catheters, and coatings for silicone breast implants. Polyurethanes comprise a family of materials with urethane linkages along the large molecular chains. Broadly, urethane/urea chemistry refers to the reactions between isocyanates/nonisocyanates and alcohols/amines that form urethane and urea bonds. Here, we will introduce different citrate-based urethane-doped elastomers developed in our lab and their applications in biomedical engineering. In addition, we will introduce waterborne polyurethane biomaterials, describe nonisocyanate urethane/urea reactions, and review nontraditional applications of isocyanate-based and nonisocyanate urethane/urea chemistry in polymer synthesis, polymer surface functionalization, polymer cross-linking, and bioconjugation.

Original languageEnglish (US)
Title of host publicationAdvances in Polyurethane Biomaterials
PublisherElsevier Inc.
Pages115-147
Number of pages33
ISBN (Electronic)9780081006221
ISBN (Print)9780081006146
DOIs
StatePublished - Feb 2 2016

Fingerprint

Urethane
Biocompatible Materials
Urea
Polyurethanes
Isocyanates
Polymers
Elastomers
Biomedical Engineering
Breast Implants
Silicones
Citric Acid
Amines
Veins
Catheters
Arteries
Alcohols

All Science Journal Classification (ASJC) codes

  • Medicine(all)
  • Health Professions(all)

Cite this

Kim, G. B., Guo, J., Hu, J., Shan, D., & Yang, J. (2016). Novel Applications of Urethane/Urea Chemistry in the Field of Biomaterials. In Advances in Polyurethane Biomaterials (pp. 115-147). Elsevier Inc.. https://doi.org/10.1016/B978-0-08-100614-6.00004-4
Kim, G. B. ; Guo, J. ; Hu, J. ; Shan, D. ; Yang, Jian. / Novel Applications of Urethane/Urea Chemistry in the Field of Biomaterials. Advances in Polyurethane Biomaterials. Elsevier Inc., 2016. pp. 115-147
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Kim, GB, Guo, J, Hu, J, Shan, D & Yang, J 2016, Novel Applications of Urethane/Urea Chemistry in the Field of Biomaterials. in Advances in Polyurethane Biomaterials. Elsevier Inc., pp. 115-147. https://doi.org/10.1016/B978-0-08-100614-6.00004-4

Novel Applications of Urethane/Urea Chemistry in the Field of Biomaterials. / Kim, G. B.; Guo, J.; Hu, J.; Shan, D.; Yang, Jian.

Advances in Polyurethane Biomaterials. Elsevier Inc., 2016. p. 115-147.

Research output: Chapter in Book/Report/Conference proceedingChapter

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Kim GB, Guo J, Hu J, Shan D, Yang J. Novel Applications of Urethane/Urea Chemistry in the Field of Biomaterials. In Advances in Polyurethane Biomaterials. Elsevier Inc. 2016. p. 115-147 https://doi.org/10.1016/B978-0-08-100614-6.00004-4