Abstract
Polyurethanes have been widely used as biomaterials since the 1960s due to their wide range of tunable physical, chemical, mechanical, biological, and medical properties. They have been used in building various applications including pacemaker lead insulation, artificial veins and arteries, catheters, and coatings for silicone breast implants. Polyurethanes comprise a family of materials with urethane linkages along the large molecular chains. Broadly, urethane/urea chemistry refers to the reactions between isocyanates/nonisocyanates and alcohols/amines that form urethane and urea bonds. Here, we will introduce different citrate-based urethane-doped elastomers developed in our lab and their applications in biomedical engineering. In addition, we will introduce waterborne polyurethane biomaterials, describe nonisocyanate urethane/urea reactions, and review nontraditional applications of isocyanate-based and nonisocyanate urethane/urea chemistry in polymer synthesis, polymer surface functionalization, polymer cross-linking, and bioconjugation.
| Original language | English (US) |
|---|---|
| Title of host publication | Advances in Polyurethane Biomaterials |
| Publisher | Elsevier Inc. |
| Pages | 115-147 |
| Number of pages | 33 |
| ISBN (Electronic) | 9780081006221 |
| ISBN (Print) | 9780081006146 |
| DOIs | |
| State | Published - Feb 2 2016 |
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All Science Journal Classification (ASJC) codes
- Medicine(all)
- Health Professions(all)
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Novel Applications of Urethane/Urea Chemistry in the Field of Biomaterials. / Kim, G. B.; Guo, J.; Hu, J.; Shan, D.; Yang, Jian.
Advances in Polyurethane Biomaterials. Elsevier Inc., 2016. p. 115-147.Research output: Chapter in Book/Report/Conference proceeding › Chapter
TY - CHAP
T1 - Novel Applications of Urethane/Urea Chemistry in the Field of Biomaterials
AU - Kim, G. B.
AU - Guo, J.
AU - Hu, J.
AU - Shan, D.
AU - Yang, Jian
PY - 2016/2/2
Y1 - 2016/2/2
N2 - Polyurethanes have been widely used as biomaterials since the 1960s due to their wide range of tunable physical, chemical, mechanical, biological, and medical properties. They have been used in building various applications including pacemaker lead insulation, artificial veins and arteries, catheters, and coatings for silicone breast implants. Polyurethanes comprise a family of materials with urethane linkages along the large molecular chains. Broadly, urethane/urea chemistry refers to the reactions between isocyanates/nonisocyanates and alcohols/amines that form urethane and urea bonds. Here, we will introduce different citrate-based urethane-doped elastomers developed in our lab and their applications in biomedical engineering. In addition, we will introduce waterborne polyurethane biomaterials, describe nonisocyanate urethane/urea reactions, and review nontraditional applications of isocyanate-based and nonisocyanate urethane/urea chemistry in polymer synthesis, polymer surface functionalization, polymer cross-linking, and bioconjugation.
AB - Polyurethanes have been widely used as biomaterials since the 1960s due to their wide range of tunable physical, chemical, mechanical, biological, and medical properties. They have been used in building various applications including pacemaker lead insulation, artificial veins and arteries, catheters, and coatings for silicone breast implants. Polyurethanes comprise a family of materials with urethane linkages along the large molecular chains. Broadly, urethane/urea chemistry refers to the reactions between isocyanates/nonisocyanates and alcohols/amines that form urethane and urea bonds. Here, we will introduce different citrate-based urethane-doped elastomers developed in our lab and their applications in biomedical engineering. In addition, we will introduce waterborne polyurethane biomaterials, describe nonisocyanate urethane/urea reactions, and review nontraditional applications of isocyanate-based and nonisocyanate urethane/urea chemistry in polymer synthesis, polymer surface functionalization, polymer cross-linking, and bioconjugation.
UR - http://www.scopus.com/inward/record.url?scp=84966778884&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84966778884&partnerID=8YFLogxK
U2 - 10.1016/B978-0-08-100614-6.00004-4
DO - 10.1016/B978-0-08-100614-6.00004-4
M3 - Chapter
AN - SCOPUS:84966778884
SN - 9780081006146
SP - 115
EP - 147
BT - Advances in Polyurethane Biomaterials
PB - Elsevier Inc.
ER -