The synthesis and characterization of a novel biodegradable elastomer, poly(1,8-octanediol-co-citric acid) (POC), for use in tissue engineering were described. Citric acid was chosen as a polyfunctional monomer because it is a non-toxic metabolic product of the body. Tubular and sponge-like POC scaffolds with inter-connected pore structures were fabricated using molds and salt leaching technique. The results suggest that POC tube scaffolds are strong enough to act as a temporary template for blood vessels engineered in vivo.
All Science Journal Classification (ASJC) codes
- Materials Science(all)
- Mechanics of Materials
- Mechanical Engineering