Women with metastatic breast cancer (MBC) face serious physiological and psychosocial challenges. The management of this chronic, incurable condition requires long-term care coordination. Traditional clinical methods do not often provide adequate and personalized support for these individuals. In this project, we aim to use smart speakers to provide supportive care interventions to improve the quality of life for women with MBC. Specifically, we have developed Nurse AMIE (Addressing Metastatic Individuals Everyday) by leveraging the Amazon Alexa to remotely deliver validated interventions. We believe that voice interactions can significantly lower the barrier to interact with remote intervention technologies for this population. In a pilot study, we deployed Nurse AMIE for 14 days over 6 women with MBC. Based on the collected data, this paper discusses the feasibility, acceptability, and future directions of Nurse AMIE. To the best of our knowledge, this is the first study to use smart speakers to support women with MBC.