@article{afa39a4fe839449aa62fd5276f994f50,
title = "OARSI Clinical Trials Recommendations: Knee imaging in clinical trials inosteoarthritis",
abstract = "Significant advances have occurred in our understanding of the pathogenesis of knee osteoarthritis (OA) and some recent trials have demonstrated the potential for modification of the disease course. The purpose of this expert opinion, consensus driven exercise is to provide detail on how one might use and apply knee imaging in knee OA trials. It includes information on acquisition methods/techniques (including guidance on positioning for radiography, sequence/protocol recommendations/hardware for magnetic resonance imaging (MRI)); commonly encountered problems (including positioning, hardware and coil failures, sequences artifacts); quality assurance (QA)/control procedures; measurement methods; measurement performance (reliability, responsiveness, validity); recommendations for trials; and research recommendations.",
author = "Hunter, {D. J.} and Altman, {R. D.} and F. Cicuttini and Crema, {M. D.} and J. Duryea and F. Eckstein and A. Guermazi and R. Kijowski and Link, {T. M.} and J. Martel-Pelletier and Miller, {C. G.} and Mosher, {T. J.} and Ochoa-Alb{\'i}ztegui, {R. E.} and Pelletier, {J. P.} and C. Peterfy and Raynauld, {J. P.} and Roemer, {F. W.} and Totterman, {S. M.} and Gold, {G. E.}",
note = "Funding Information: Dr Hunter is supported by an NHMRC Health Practitioner Fellowship. Dr Gold is supported by an NIH K24 Grant ( AR062068 ) and RO1 ( EB002524 ). Funding Information: Johanne Martel-Pelletier & Jean-Pierre Pelletier – receives honoraria from ArthroLab/ArthroVision, Bioiberica, Elanco, Ferring, Merck, Pfizer, Servier, TRB Chemedica. Has grants from The Arthritis Society (as co-investigators), Canadian Institutes of Health Research (CIHR) (as co-investigator). Has investment in non-medical industry at ArthroLab/ArthroVision and is a Shareholder. Holds a volunteered lecturer position at the ESCEO13-IOF European Congress on Osteoporosis and Osteoarthritis (travel grant). Funding Information: Garry E. Gold receives honoraria as a consultant from Zimmer Inc., Isto, Inc. and Boston Scientific. Has a grant from GE Healthcare for improved MR Systems and one from the NIH for advanced MRI of Osteoarthritis. Funding Information: David Hunter has royalties from DJO for a patent granted for a patellofemoral buttress. Has grants from the NIH, Australian Research Council and NHMRC. Associate Editor for Osteoarthritis and Cartilage. Funding Information: Flavia Cicuttini – Receives honoraria from Jansen. Has grants from the NHMRC for Statin RCT, Zolendronic Acid RCT and ACL study. Holds a volunteered paid position in Repatriation Medical Authority as a Medical Officer and as an Associate Editor in the BMC Musculoskeletal Journal, ART Journal. Publisher Copyright: {\textcopyright} 2015 Osteoarthritis Research Society International. Published by Elsevier Ltd.",
year = "2015",
doi = "10.1016/j.joca.2015.03.012",
language = "English (US)",
volume = "23",
pages = "698--715",
journal = "Osteoarthritis and Cartilage",
issn = "1063-4584",
publisher = "W.B. Saunders Ltd",
number = "5",
}