TY - JOUR
T1 - Obesity, physical activity and the development of metabolic syndrome
T2 - The atherosclerosis risk in communities study
AU - Cheriyath, Pramil
AU - Duan, Yinkang
AU - Nambiar, Lakshmi
AU - Liao, Daunping
N1 - Funding Information:
The ARIC Study is conducted and supported by the National Heart, Lung, and Blood Institute (NHLBI) in collaboration with the ARIC Investigators. The authors thank the NHLBI for providing the public use data for this investigation. The authors thank the staff and participants of the ARIC study for their important contributions. We also thank Laurie Schwing, MLS, for advice, guidance and editorial support for this project. The authors did not receive any source of funding for this project from anyone. There is no conflict of interest to report.
PY - 2010/6
Y1 - 2010/6
N2 - The objective of this study is to determine the impact of body weight and physical activity on the development of metabolic syndrome (MetS). and methods We used the public use data from the Atherosclerosis Risk in Communities study. From the baseline cohort, we identified, as the study population, 9359 individuals who did not have MetS and who completed the second follow-up examination in 1993-1995. In 6 years of follow-up, 1970 individuals (25%) developed MetS. Compared with normal weight group [body mass index (BMI) <25 kg/m2], the odds ratios [95% confidence interval (CI)] of incident MetS were 2.81 (95% CI: 2.50-3.17) and 5.24 (95% CI: 4.50-6.12) for the overweight (BMI: 25-30 kg/m2) and the obese groups (BMI ≥ 30 kg/m2), respectively. Compared with persons in the lowest quartile of leisure-time physical activity, the odds ratios (95% CI) of incident MetS were 0.80 (95% CI: 0.71-0.91) and 0.92 (95% CI: 0.81-1.04) for persons in the highest and the middle quartiles of leisure-time physical activity, respectively. Our results indicated that at any level of physical activity, there is a graded increase in the risk of incident MetS with an increase in BMI, in contrast to a lack of graded association between physical activity and the incidence of MetS in all categories of BMI. This study highlights the need to target obesity more than physical activity in preventing the development of MetS. Eur J Cardiovasc Prev Rehabil 17:309-313.
AB - The objective of this study is to determine the impact of body weight and physical activity on the development of metabolic syndrome (MetS). and methods We used the public use data from the Atherosclerosis Risk in Communities study. From the baseline cohort, we identified, as the study population, 9359 individuals who did not have MetS and who completed the second follow-up examination in 1993-1995. In 6 years of follow-up, 1970 individuals (25%) developed MetS. Compared with normal weight group [body mass index (BMI) <25 kg/m2], the odds ratios [95% confidence interval (CI)] of incident MetS were 2.81 (95% CI: 2.50-3.17) and 5.24 (95% CI: 4.50-6.12) for the overweight (BMI: 25-30 kg/m2) and the obese groups (BMI ≥ 30 kg/m2), respectively. Compared with persons in the lowest quartile of leisure-time physical activity, the odds ratios (95% CI) of incident MetS were 0.80 (95% CI: 0.71-0.91) and 0.92 (95% CI: 0.81-1.04) for persons in the highest and the middle quartiles of leisure-time physical activity, respectively. Our results indicated that at any level of physical activity, there is a graded increase in the risk of incident MetS with an increase in BMI, in contrast to a lack of graded association between physical activity and the incidence of MetS in all categories of BMI. This study highlights the need to target obesity more than physical activity in preventing the development of MetS. Eur J Cardiovasc Prev Rehabil 17:309-313.
UR - http://www.scopus.com/inward/record.url?scp=77954033096&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=77954033096&partnerID=8YFLogxK
U2 - 10.1097/HJR.0b013e32833189b8
DO - 10.1097/HJR.0b013e32833189b8
M3 - Article
C2 - 20300002
AN - SCOPUS:77954033096
SN - 2047-4873
VL - 17
SP - 309
EP - 313
JO - European Journal of Preventive Cardiology
JF - European Journal of Preventive Cardiology
IS - 3
ER -