Observation of polymers and biological molecules on surfaces by scanning tunneling microscopy

H. Zareie, K. Piskin, Kaitian Xu, S. Mutlu, E. Piskin

Research output: Contribution to journalConference article

Abstract

The paper presents the scanning tunneling microscopic (STM) observations of several natural and synthetic macromolecules on highly oriented pyrolithic graphite and mica surfaces. The interaction of DNA molecules (from both healthy and cancerogeneous cells) and calcium ions were observed. The development of enzyme electrodes in which glucose oxidase and albumin are used in a crosslinked form was also studied in order to get a better understanding of the effects of crosslinking on the molecular conformations of biological molecules. STM images of copolymer micelles and micelles of commercially available emulsifiers were also obtained and studied.

Original languageEnglish (US)
JournalArtificial Cells, Blood Substitutes, and Immobilization Biotechnology
Volume22
Issue number5
StatePublished - Nov 1 1994
EventProceedings of the 11th Congress of the International Society for Artificial Cells, Blood Substitutes and Immobilization Biotechnology, (ISABI) - Boston, MA, USA
Duration: Jul 24 1994Jul 27 1994

Fingerprint

Scanning Tunnelling Microscopy
Micelles
Scanning tunneling microscopy
Polymers
Observation
Enzyme electrodes
Scanning
Molecular Conformation
Glucose Oxidase
Glucose oxidase
Molecules
Graphite
Mica
Biosensing Techniques
Macromolecules
Crosslinking
Conformations
Albumins
Calcium
DNA

All Science Journal Classification (ASJC) codes

  • Biotechnology
  • Biomedical Engineering

Cite this

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Observation of polymers and biological molecules on surfaces by scanning tunneling microscopy. / Zareie, H.; Piskin, K.; Xu, Kaitian; Mutlu, S.; Piskin, E.

In: Artificial Cells, Blood Substitutes, and Immobilization Biotechnology, Vol. 22, No. 5, 01.11.1994.

Research output: Contribution to journalConference article

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AU - Piskin, K.

AU - Xu, Kaitian

AU - Mutlu, S.

AU - Piskin, E.

PY - 1994/11/1

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