Occupation and pancreatic cancer risk in Louisiana

Roni T. Falk, Linda Williams Pickle, Elizabeth T. Fontham, Pelayo Correa, Anne Morse, Vivien Chen, Joseph J. Fraumeni

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Abstract

To study the relation of occupational exposures and pancreatic cancer, we evaluated data from males (198 cases and 209 controls) participating in a hospital‐based case‐control study conducted in a high‐risk area of Louisiana between 1979 and 1983. The questionnaire obtained information on lifetime occupational history, as well as dietary, smoking, and drinking habits and demographic characteristics. After adjustment for smoking and dietary patterns, white collar occupations showed consistent elevations in risk, whereas associations for other occupations were in general unremarkable. Although not significantly elevated, risks for truck drivers (OR = 1.7) and those with long‐term employment in machine repair or as mechanics were suggestive (OR = 2.5). No association was found for jobs in oil refining or oil and gas extraction (ORs were 0.5 and 0.4, respectively), although risks were slightly elevated for long‐term workers in the chemical processing industry (OR = 1.2). While these associations deserve further study, our findings are consistent with results of other studies which do not suggest that occupational exposures are important determinants of pancreatic cancer.

Original languageEnglish (US)
Pages (from-to)565-576
Number of pages12
JournalAmerican Journal of Industrial Medicine
Volume18
Issue number5
DOIs
StatePublished - Jan 1 1990

All Science Journal Classification (ASJC) codes

  • Public Health, Environmental and Occupational Health

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    Falk, R. T., Pickle, L. W., Fontham, E. T., Correa, P., Morse, A., Chen, V., & Fraumeni, J. J. (1990). Occupation and pancreatic cancer risk in Louisiana. American Journal of Industrial Medicine, 18(5), 565-576. https://doi.org/10.1002/ajim.4700180507