Occupational contact dermatitis in North American production workers referred for patch testing: Retrospective analysis of cross-sectional data from the North American contact dermatitis group 1998 to 2014

Erin M. Warshaw, Solveig L. Hagen, Joel G. DeKoven, Kathryn A. Zug, Denis Sasseville, Donald V. Belsito, Matthew J. Zirwas, Joseph F. Fowler, James S. Taylor, Anthony F. Fransway, Vincent A. DeLeo, James G. Marks, Melanie D. Pratt, Howard I. Maibach, C. G.Toby Mathias

Research output: Contribution to journalArticle

11 Scopus citations

Abstract

Background: Little is known about the epidemiology of contact dermatitis in production workers (PWs). Objective: The aims of this study were to estimate the prevalence of contact dermatitis and characterize clinically relevant and occupationally related allergens among North American PWs undergoing patch testing. Methods: This was a retrospective cross-sectional analysis of North American Contact Dermatitis Group data from 1998 to 2014. Results: Of 39,332 patch-tested patients, 2732 (7.0%) were PWs. Among PWs, most were men (62.4%) and white (83.9%). A history of childhood eczema was uncommon (11.3%). Prevalent occupations included machine operators (27.3%); fabricators, assemblers, and hand-working occupations (16.8%); and precision metalworking occupations (16.1%). The most frequent sites of dermatitis were the hands (53.8%) and arms (29.4%), which were significantly more commonly affected compared with non-PWs (P G 0.0001). Occupationally related skin disease, allergic contact dermatitis, and irritant contact dermatitis were also significantlymore common in PWs (49.9%vs 10.6%, 58.9%vs 53.7%, and 32.7%vs 25.7%, respectively; all Ps G 0.0001). Epoxy (15.3%), thiuram mix (8.3%), carbamix (8.1%), formaldehyde (6.3%), and cobalt (5.9%)were themost frequent occupationally related allergens.The top allergensources includedadhesives/glues (16.0%), metalworking fluids/cutting oils (6.8%), and coatings (6.3%). Conclusions: Production workers had a high rate of occupationally related skin disease, as well as irritant and allergic contact dermatitis. Involvement of exposed body areas was common. Frequently identified allergens included adhesives/glues, rubber accelerators, metals, and preservatives.

Original languageEnglish (US)
Pages (from-to)183-194
Number of pages12
JournalDermatitis
Volume28
Issue number3
DOIs
StatePublished - Jun 1 2017

All Science Journal Classification (ASJC) codes

  • Immunology and Allergy
  • Dermatology

Fingerprint Dive into the research topics of 'Occupational contact dermatitis in North American production workers referred for patch testing: Retrospective analysis of cross-sectional data from the North American contact dermatitis group 1998 to 2014'. Together they form a unique fingerprint.

  • Cite this

    Warshaw, E. M., Hagen, S. L., DeKoven, J. G., Zug, K. A., Sasseville, D., Belsito, D. V., Zirwas, M. J., Fowler, J. F., Taylor, J. S., Fransway, A. F., DeLeo, V. A., Marks, J. G., Pratt, M. D., Maibach, H. I., & Mathias, C. G. T. (2017). Occupational contact dermatitis in North American production workers referred for patch testing: Retrospective analysis of cross-sectional data from the North American contact dermatitis group 1998 to 2014. Dermatitis, 28(3), 183-194. https://doi.org/10.1097/DER.0000000000000277