Odour-plume dynamics influence file brain's olfactory code

Neil J. Vickers, Thomas A. Christensen, Thomas C. Baker, John G. Hildebrand

Research output: Contribution to journalArticle

189 Scopus citations

Abstract

The neural computations used to represent olfactory information in the brain have long been investigated. Recent studies in the insect antennal lobe suggest that precise temporal and/or spatial patterns of activity underlie the recognition and discrimination of different odours, and that these patterns may be strengthened by associative learning. It remains unknown, however, whether these activity patterns persist when odour intensity varies rapidly and unpredictably, as often occurs in nature. Here we show that with naturally intermittent odour stimulation, spike patterns recorded from moth antennal-lobe output neurons varied predictably with the fine-scale temporal dynamics and intensity of the odour. These data support the hypothesis that olfactory circuits compensate for contextual variations in the stimulus pattern with high temporal precision. The timing of output neuron activity is constantly modulated to reflect ongoing changes in stimulus intensity and dynamics that occur on a millisecond timescale.

Original languageEnglish (US)
Pages (from-to)466-470
Number of pages5
JournalNature
Volume410
Issue number6827
DOIs
StatePublished - Mar 22 2001

All Science Journal Classification (ASJC) codes

  • General

Fingerprint Dive into the research topics of 'Odour-plume dynamics influence file brain's olfactory code'. Together they form a unique fingerprint.

  • Cite this

    Vickers, N. J., Christensen, T. A., Baker, T. C., & Hildebrand, J. G. (2001). Odour-plume dynamics influence file brain's olfactory code. Nature, 410(6827), 466-470. https://doi.org/10.1038/35068559