Old and new: Appropriate dosing for neonatal antifungal drugs in the nursery

Jessica Ericson, Paolo Manzoni, Daniel K. Benjamin

Research output: Contribution to journalReview article

5 Scopus citations

Abstract

Candida infections are a source of significant mortality and morbidity in the neonatal intensive care unit. Treatment strategies continue to change as additional antifungals become available and studies in neonates are performed. Amphotericin B deoxycholate has been favored for many years, but fluconazole has the most data supporting its use in neonatal Candida infections and is often employed for prophylaxis as well as treatment. Voriconazole and posaconazole have limited utility in the nursery and are rarely used. The echinocandins are increasingly administered for invasive Candida infections, although higher doses are required in neonates than in older children and adults.

Original languageEnglish (US)
Pages (from-to)S25-S27
JournalEarly Human Development
Volume89
Issue numberSUPPL.1
DOIs
StatePublished - Jun 2013

All Science Journal Classification (ASJC) codes

  • Pediatrics, Perinatology, and Child Health
  • Obstetrics and Gynecology

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