Oligosachharide modified biomimetic surfactant polymer for non-thrombogenic interface applications: Platelet Adhesion Studies

Anirban Sen Gupta, Emily Link, Shuwu Wang, Kandice Kottke-Marchant, Roger E. Marchant

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Platelet adhesion of oligosachharide modified biomimetic surfactant polymer for non-thrombogenic interface applications was investigated. Low-molecular weight poly(vinyl amine) (PVAm) with well-defined structure and narrow polydispersity was synthesized from poly(N-vinylformamide). Blood was drawn from healthy, aspirin-refraining adult donors into 3.8% sodium citrate anticoagulant in a 9:1 ratio. The number of adhered platelets per mm 2 was found to be significantly lower for surfactant-coated disks compared with uncoated disks in both platelet rich plasma (PRP) and human whole blood (WB).

Original languageEnglish (US)
Title of host publication2004 AIChE Annual Meeting, Conference Proceedings
Pages6377-6379
Number of pages3
StatePublished - 2004
Event2004 AIChE Annual Meeting - Austin, TX, United States
Duration: Nov 7 2004Nov 12 2004

Other

Other2004 AIChE Annual Meeting
CountryUnited States
CityAustin, TX
Period11/7/0411/12/04

All Science Journal Classification (ASJC) codes

  • Engineering(all)

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