On-chip single nanoparticle detection and sizing by mode splitting in an ultrahigh-Q microresonator

Jiangang Zhu, Sahin Kaya Ozdemir, Yun Feng Xiao, Lin Li, Lina He, Da Ren Chen, Lan Yang

Research output: Contribution to journalArticle

709 Scopus citations


The ability to detect and size individual nanoparticles with high resolution is crucial to understanding the behaviour of single particles and effectively using their strong size-dependent properties to develop innovative products. We report real-time, in situ detection and sizing of single nanoparticles, down to 30nm in radius, using mode splitting in a monolithic ultrahigh-quality-factor (Q) whispering-gallery-mode microresonator. Particle binding splits a whispering-gallery mode into two spectrally shifted resonance modes, forming a self-referenced detection scheme. This technique provides superior noise suppression and enables the extraction of accurate particle size information with a single-shot measurement in a microscale device. Our method requires neither labelling of the particles nor a priori information on their presence in the medium, providing an effective platform to study nanoparticles at single-particle resolution.

Original languageEnglish (US)
Pages (from-to)46-49
Number of pages4
JournalNature Photonics
Issue number1
StatePublished - Jan 1 2010

All Science Journal Classification (ASJC) codes

  • Electronic, Optical and Magnetic Materials
  • Atomic and Molecular Physics, and Optics

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