Oncogenic osteomalacia of the cervical spine: A rare case of curative resection and reconstruction. Case report

Murtaza Akhter, Patrick A. Sugrue, Rick Bains, Yevgeniy A. Khavkin

Research output: Contribution to journalArticlepeer-review

10 Scopus citations

Abstract

Oncogenic osteomalacia (OO) is a rare paraneoplastic syndrome, with only 100 reported cases in the literature. The majority of OO-associated mesenchymal tumors are due to a lesion called phosphaturic mesenchymal tumor, mixed connective tissue (PMTMCT) variant. There have been only 6 reported cases of OO of the spine. With this paper the authors present a case of OO of the cervical spine in a patient who initially presented with multiple pathological fractures of unknown cause, and who eventually underwent staged C-5 spondylectomy followed by circumferential stabilization. Resection of the cervical lesion led to resolution of his hypophosphatemia and prevention of any further pathological fractures. The authors describe a rare cervical neoplasm, its treatment, and review the literature on this rare bony pathological entity.

Original languageEnglish (US)
Pages (from-to)453-456
Number of pages4
JournalJournal of Neurosurgery: Spine
Volume14
Issue number4
DOIs
StatePublished - Apr 2011

All Science Journal Classification (ASJC) codes

  • Surgery
  • Neurology
  • Clinical Neurology

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